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L A Ruiatkina

Publications and source records attributed to L A Ruiatkina.

9 recordsLinked to original sources
PubMed2006

[Current views about the role of purin metabolism disorders in patients with arterial hypertension and losartan potentialities].

The analysis of correlation between cardiovascular diseases and hyperuricaemia as a component of methabolic syndrome has been performed; the emphasis has been done on predominant mechanism of its development -- reduction of renal clearance. The need for primary prophylaxis of stroke with a help of safe metabolically antihypertensive therapy has been substantiated. The results of secondary analysis of LIFE study represented its results on effective primary prophylaxis of stroke depending on the dynamic of serum uric acid levels taking into account uricosuric effect of losartan have been discussed.

Angiotensin-Converting Enzyme Inhibitors↗
PubMed2005

[Hormone-producing function of the ovaries in young and middle-aged women with arterial hypertension and coronary heart disease].

The study demonstrates that arterial hypertension itself, judging by main anthropometric variables such as body weight index and waist to hip ratio, together with the estrogen-producing function of the ovaries, evaluated by measuring follicle-stimulating hormone levels, contributes substantially to the forming of abdominal obesity in normo- and hypertensive women. All the above confirms close correlation between hemodynamic and metabolic disturbances which eventually result in coronary heart disease in young and middle-aged women.

Adult↗
PubMed2004

[On the possible prooxidant role of insulinemia in formation of metabolic syndrome in men and women.].

Levels of basal insulinemia, malondialdehyde (an index of oxidative stress) and some metabolic parameters were studied in 143 men and 83 women aged 48.3+/-0.7 years with incomplete metabolic syndrome: hypertension, abdominal obesity, dyslipoproteinemia with normoglycemia. Basal insulinemia correlated significantly with malondialdehyde levels both in men and women. Slose relationship was also found between basal insulinemia and waist circumference.

Female↗
PubMed2002

[Predictive value of insulin-glucose homeostasis markers in patients with metabolic syndrome X].

AIM: To clarify informative value of secretory ability of pancreatic beta-cells and correspondence of insulin values to glycemia in the course of standard glucose tolerance test (GTT) in detection of insulin-resistance in patients with arterial hypertension (AH) to verify metabolic syndrome (MS). MATERIAL AND METHODS: Correlation and factor analyses were performed of correlations between glycemia, immunoreactive insulin (IRI), C-peptide, glucose/IRI in the course of GTT in 111 AH patients divided into groups by the sum of metabolic disturbances. RESULTS: The greatest number of correlations were seen for glucose/IRI fasting index. According to the factor analysis, changed sensitivity to insulin and hyperinsulinemia are the first stage of metabolic disturbances in AH irrespective of body mass. In obesity the number of the above correlations is maximal. Multivariance analysis has shown significant differences between AH patients and healthy subjects irrespective of body mass and glucose tolerance. CONCLUSION: Basal index glucose/IRI < 6 relative units is informative in all the studied variants of metabolic syndrome as regards insulin resistance.

Adult↗