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Biomedical subjects

L Abraham-Inpijn

Publications and source records attributed to L Abraham-Inpijn.

At least 73 records · Page 4Linked to original sources
PubMed1982

Predisposing factors in Bell's palsy: a clinical study with reference to diabetes mellitus, hypertension, clotting mechanism and lipid disturbance.

The purpose of this study was to assess the frequency of risk factors for vascular disease like hypertension, lipid disturbances and diabetes mellitus in a group of patients with Bell's palsy. These patients were compared to patients with a peripheral facial paralysis of known origin. We did find a statistically significant difference between the Bell's palsy patients and their controls for cardio-vascular variables only. Hypertension proved to be by far the most important single discriminating variable.

Adolescent↗
PubMed1980

Wegener's granulomatosis, serous otitis media and sinusitis.

A description is given of two patients suffering from Wegener's granulomatosis. The first manifestations were an acute sinusitis and an acute otitis media, with sterile granulomatosis tissue in the diseased organs, high fever and joint complaints. Thereafter the general symptoms of the disease showed themselves. The immediate response to treatment with cytotoxic and corticosteroid drugs was encouraging.

Adult↗
PubMed1979

Critical evaluation of low-dose heparin in laryngectomy.

In a clinical trial thromboembolic prophylaxis with subcutaneous low-dose heparin was given to 20 patients admitted for surgery on the larynx. All patients (40 totally) had a malignancy. The study was not primarily directed on the antithrombotic effect, but on complication factors. In the control group pulmonary embolism was found four times, but not in the group of patients receiving heparin. No increase of blood loss in the heparin group appeared, although this group included very difficult operations. No complications were seen to arise from the injections of the heparin.

Female↗
PubMed1978

Alpha-foetoprotein during chemically induced hepatocellular carcinoma in rats.

During induction of hepatocellular carcinoma (HCC) in rats with 3'MeDAB (3'methyl-dimethyl-aminoazobenzene) and Aflatoxin B1 alpha-foetoprotein (AFP) could already be demonstrated in the serum in the early phase of carcinogen administration. In this period the liver showed livercell necrosis but no tumour formation. The AFP level in the induction phase was correlated with the degree of livercell necrosis. The detection of AFP during the induction period is of importance as it is followed by a high frequency of liver tumours in later phases. The AFP concentration in the tumour phase was not related in any histological feature of the tumour; however, the mean AFP concentration in cases of HCC combined with cirrhosis was much higher than in cases of HCC without cirrhosis. Some rats with HCC showed AFP-negative sera, but AFP-positive bile.

Aflatoxins↗
PubMed1975

Effect of low-dose heparin on incidence of postoperative thrombosis in orthopaedic patients.

In a double-blind study, using matched controls, thrombo-embolic prophylaxis with subcutaneous low-dose heparin was studied in 25 patients admitted for orthopaedic surgery. Deep vein thrombosis (DVT) was detected by clinical assessment and by the 125I-fibrinogen leg-scanning technique. As a control the T-1/2 of the 125I-fibrinogen was measured. Six of the 13 patients in the control group and one in the heparin-treated group developed deep vein thrombosis within the first eight postoperative days.

Aged↗
PubMedDate not supplied

Detecting the medically compromised patient in dentistry by means of the medical risk-related history. A survey of 29,424 dental patients in The Netherlands.

BACKGROUND: This study focuses on the detection of medically compromised dental patients in the Netherlands by means of a validated patient-administered medical risk-related history (MRRH). Due to social changes and scientific innovations in the past decade, more medically compromised patients will be needing special dental treatment. METHODS: The medical problems of 29,424 dental patients (age 18 years and over) from 50 dental practices in the Netherlands were registered by means of the MRRH. The patients were classified according to the ASA risk-score system, which was modified for dental treatment. An inventory of the number and nature of medical problems and the modified ASA risk score was drawn up in relation to dental treatment and age. RESULTS: The average age of the patients was 37.1 +/- 13.5 years. According to the current guidelines, dental treatment must be modified if the patient has an ASA score of III or IV. A relatively high percentage of patients ages 65-74 (23.9%) and 75 or over (34.9%) did have an ASA score of III or IV. Furthermore, the medical problems were classified into 10 categories, and the relationship to age was examined. The conditions that increased with age were hypertension and cardiovascular, neurological, endocrinological, infectious, and blood diseases. CONCLUSIONS: For the dental practice, these results mean that the MRRH can play an important role in adapting dental treatment to the specific needs of patients. This is especially important in the case of elderly patients.

Adolescent↗
PubMedDate not supplied

Non-invasive 27-hour blood pressure registration including dental checkups in some dental practices.

The study involved 53 patients aged 18 to 67 (mean age 38.8, SD 13.6), 26 male and 27 female, who were monitored by means of a 27-hour non-invasive ambulant blood pressure registration, using the Oxford Monitoring System. All patients had been under dental supervision by the same dentist for more than one year, and were familiar with the procedure during checkups. This study showed a significant rise in systolic blood pressure (8.6 mmHg) and a tendency towards increased diastolic pressure (2.9 mmHg) during dental checkups in comparison with the values recorded 24 hours earlier during normal daily activity. These results were independent of the blood pressure classification (normotensive, borderline or hypertensive) of the patients and are comparable to the increases measured during a visit to the GP. Neither the sex nor the manner of the dentist had any significant influence on either the systolic or diastolic pressure values during the checkup. Nor did the phobic level of the patients significantly influence blood pressure values during the dental checkup. On the basis of the results of this study, it may be concluded that regardless of whether the patient is phobic or non-phobic, and regardless of the sex and manner of the dentist, blood pressure measurements taken during dental checkups are reliable and can be used for referral decisions.

Adolescent↗