Biomedical subjects

L Aebi

Publications and source records attributed to L Aebi.

3 recordsLinked to original sources

PubMed2006

Ultrasonic surface crack characterization on complex geometries using surface waves.

The characterization of surface cracks on complex geometries using surface waves is investigated numerically and experimentally. The specimen geometry is implemented in a finite difference code by approximation of the contour using a Cartesian grid. In the experiments the out-of-plane surface displacement is measured by means of a heterodyne laser interferometer. Good agreement is shown by comparison of the calculated out-of-plane displacement with experimental results for both cracked and non-cracked specimens. The crack depth is measured down to a size of 0.7 times the surface wavelength using a time delay approach. The many Rayleigh pulses propagating after the crack can be separated from the other modes by a filtering procedure based on the surface wave propagation velocity. Only a detailed analysis of the scattering phenomenon using the simulation allows an identification of the transmitted pulse required for crack depth measurement. Application of the method to a specimen with a real fatigue crack shows a systematical error possibly due to the inclined crack profile.

Journal Article↗

PubMed2005

Influence of vedaprofen (Quadrisol) on quality and freezability of stallion semen.

The objective of this study was to evaluate the effect of the non-steroidal anti-inflammatory drug (NSAID) vedaprofen (Quadrisol) on quality and freezability of stallion semen. Experiments were performed using 22 Franches Montagnes stallions from the National Stud in Avenches (Switzerland) randomly divided into a control and test group. Vedaprofen was given orally to all stallions of the test group at the recommended therapeutic dose (initial dose of 2mg/kg followed by 1mg/kg body weight every 12h) for 14 days. Control animals received the same amount of carrier substance. During treatment, blood samples of five stallions in both test and control group were collected for PGF(2 alpha)-metabolite (PG-metabolite) determination. Ejaculates from all stallions were collected and cryopreserved weekly for 14 weeks from September to December. Concentrations of PG-metabolite, PGF and PGE were measured in the seminal plasma of ejaculates collected 2 weeks before, during and 2 weeks after treatment. In fresh semen the volume, concentration, motility and number of normal sperm and sperm with major defects (acrosome defects, abnormal heads, nuclear vacuoles, proximal droplets, midpiece defects) were evaluated. In frozen-thawed semen samples motility as well as viability (SYBR-14/PI) were tested and the hypoosmotic swelling test (HOS) was performed. Results demonstrate that vedaprofen had no effect on blood plasma concentration of PG-metabolite but significantly inhibited both, PGF and PGE concentrations in seminal plasma. Furthermore, all quality parameters in fresh and frozen-thawed semen were not affected by vedaprofen treatment but the time of semen collection had a significant (P<0.05) effect on motility, normal sperm and sperm with nuclear vacuoles in fresh semen.

Animals↗

PubMed2002

[Horse breeding: genetic tests for the coat colors chestnut, bay and black. Results from a preliminary study in the Swiss Freiberger horse breed].

Coat color played an important role during domestication and formation of breeds. Livestock breeders often had special preferences for particular color phenotypes because they believed them to be associated with performance or fitness traits. Socio-cultural reasons might have had an influence on color selection as well. Recently genetic tests on DNA level got available to genotype in any individual horse for basic horse coat colors (chestnut, bay, black). In particular, hidden carriers of the recessive chestnut and black allele are recognizable with these tests. A sample of 162 Franches-Montagnes horses from Switzerland was genotyped for the alleles for chestnut and black. The analysis of allele frequencies revealed a high prevalence of the chestnut allele and a low frequency of the black allele in this population. Rare colors are in demand on the market. The statistical analysis of 1369 offspring from five stallions indicate, that darker shades of basic color phenotypes (dark chestnut, dark bay) follow a recessive mode of inheritance in the Franches-Montagnes horse breed.

Animals↗