[Corticobasal degeneration. Description of a consanguineous case].
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Biomedical subjects
Publications and source records attributed to L Alvarez González.
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INTRODUCTION: There are many, diverse nosological entities with the common factor of the genesis of cortical evoked potentials of great amplitude, commonly known as giant evoked potentials. In most cases they are conditions with the common clinical condition of myoclonic of cortical origin, such as progressive myoclonic epilepsy, generalized idiopathic epilepsy, myoclonias of toxic, infectious or postanoxic origin. Giant potentials have been shown both in studies of focal hemisphere lesions and in some cases of patients with corticobasal degeneration. OBJECTIVE: The aim of this paper was to show, by presenting interesting cases, some of the conditions mentioned and to review some concepts concerning the mechanisms which may be involved in the production of these electrophysiological responses. PATIENTS AND METHODS: We studied 6 patients aged between 2 and 22 years, in whom multimodal evoked potentials, electroencephalograms and imaging studies had been done. RESULTS: Giant somatosensory potentials were shown in the patients with obvious myoclonia. Visual potentials of great amplitude were common to the other patients presented, with or without myoclonia. CONCLUSION: Giant evoked potentials respond to a state of cortical hyperexcitability which may have various causes.
BACKGROUND: To evaluate the efficiency of the school health test, by studying; the number of unknown anomalies detected; the number of children who went to confirm the anomalies; and the number of anomalies confirmed. METHODS: A descriptive observational study, with a subsequent followup, aimed at all students tested from the first, fifth and eighth years of EGB from the six schools in the basic area of "Molino de la Vega" in Huelva (714 in total). RESULTS: A total of 172 anomalies were detected (24% of the examined). Of those, 133 (77.3%) were followed and 112 (84.2%) came back to confirm the diagnosis, being the highest percentage (100%) for empty scrotum and the lowest (75%) for somatometric anomalies. A number of 73 (79.76%) of the anomalies detected were confirmed, reaching the maximum for visual alterations (86.48%) and the minimum for raquis deviations (65.21%). Of the children examined a 10.22% had anomalies not detected before. CONCLUSIONS: The school test proved highly efficient. Given the high number of anomalies detected in our basic health area, the percentage of children who went to confirm the diagnosis together with the high percentage of anomalies confirmed.