PubMed HealthSearch

Biomedical subjects

L Asfar

Publications and source records attributed to L Asfar.

3 recordsLinked to original sources

Scanning slit delivery system.

We describe the structure and function of a delivery system designed for use with an argon fluoride excimer laser for corneal surgery. The basic principle of the delivery system is to shape the laser beam with a slit mask to a defined configuration. The image of the slit is moved across the cornea in a mathematically defined pattern to ablate a given amount of tissue, creating a new anterior radius of curvature for the cornea. The location of the beam on the cornea is determined by a rotating dove prism and a translating spherical lens, each of which is controlled by computer-regulated servomotors. The system is versatile and can be used for laser myopic or hyperopic keratomileusis, for correction of astigmatism by surface ablation, for creation of radial or transverse linear cuts, for excision of corneal buttons, and for uniform lamellar corneal smoothing procedures. The delivery system is currently used in the laboratory for the ablation of nonhuman primate corneas.

Animals

Excimer laser keratectomy for myopia with a rotating-slit delivery system.

We performed argon fluoride excimer laser (193-nm) superficial keratectomy for myopia on human donor eyes and on a resected corneal disc. The laser beam was shaped by a rotating slit to produce a circular ablation 7.5 mm in diameter, with a mathematically defined profile to correct myopia. The fluence at the surface of the cornea was 200 mJ/cm2; the laser was fired at 20 Hz. Each 4.5-mJ laser pulse etched a 0.17-micron deep image of the slit in the cornea. Since the slit moved (0.03 Hz), each successive pulse etched an area adjacent to the previous one, reducing damage from repetitive pulses striking the same area. The slit scanned the cornea many times and the summation of these individual ablations produced the smooth myopic ablation profile, as shown by computerized keratographs and light and electron microscopy.

Cornea