Biomedical subjects

L Aulisa

Publications and source records attributed to L Aulisa.

41 records · Page 3Linked to original sources

PubMedDate not supplied

[Pott disease: current diagnostic and therapeutic approaches].

Spinal tuberculosis, or Pott's disease, has been known since ancient times; it was a common orthopaedic illness until 1950, but the progress of specific therapies confined it to third word countries; its resurgency in recent years in developed countries is due to drug resistance, immigration from endemic areas, and an increase in immunodeficient patients. Spinal disease is found in about 1% of all tuberculosis cases. Modern treatment consists of a diagnostic phase, based on clinical findings and imaging exams, and of a medical and surgical therapy. Our patients have been treated with a three antibiotic drugs scheme, and underwent early surgical treatment, in order to assure the curettage of the lesion and obtain spine stabilization, so as to avoid spinal deformity.

Humans↗

PubMedDate not supplied

[An effective method to prevent deep venous thrombosis in total hip arthroplasty: a study in patients with and without risk factors for thrombotic disease].

PURPOSE: The aim of this study was to determine a safe and effective method of prophylaxis for thromboembolis diseases after THA. MATERIALS AND METHODS: This study was conducted on 157 patients consecutively admitted to our Department of Orthopedics to undergo elective THA from October 2000 o May 2001. We have preoperatively investigated plasma levels of homocysteine, AT III activity, Fibrinogen levels, Anticardiolipin antibodies, and circulating vWFag D-dimer levels were measured by Asserachrom D-dimer ELISA preoperatively and on day 4 postoperatively. Thromboprophylactic regimen was based on a prolonged subcutaneous administration of nadroparin (for 40 days after surgery) and was used in all patients, with a dose based on body weight. Compression ultrasonography was udes as screening test for the diagnosis of deep venous thrombosis and performed in each patient on postoperative day 4, 15, and 30. RESULTS: Although all patients enrolled in this study showed increased risk for thrombotic disease, none oh them developed either symptomatic or asymptomatic deep venous thrombosis. No complications were observed, including major bleeding or abnormalities of laboratory tests. CONCLUSIONS: Our study indicates that prolonged thromboprophylaxis with nadroparin for 40 days postoperatively, associated with early mobilization, is an effective and safe protocol of antithrombotic prophylaxis in patients operated for THA with and without risk factors for thrombotic disease.

Anticoagulants↗

PubMedDate not supplied

[Pulmonary scintigraphy with radioaerosol in idiopathic scoliosis].

The study of respiratory function is of key importance for the clinical evaluation of patients with idiopathic scoliosis. Such study has been traditionally based on classical pulmonary function tests and arterial blood gas analysis. However, neither procedure gives any information on the topographical distribution of abnormalities, and both might be suboptimal as far as sensitivity is concerned. The preliminary results obtained with radioaerosol lung scintigraphy in 11 patients with scoliosis are here presented. They lead to the conclusion that radioaerosol lung scintigraphy, besides being an useful adjunct to more traditional diagnostic procedures, can yield unique information on the localization of convective ventilation derangements induced by the dynamic abnormalities of the rib cage.

Adolescent↗

PubMedDate not supplied

Surgery of osteoarticular tuberculosis.

Because of the increasing incidence of tuberculosis consequent on the increasing number of patients with drug-related or HIV-induced immunosuppression, the problems of the invasive or noninvasive treatment of osteoarticular tuberculosis have come up again. While the approach aimed at the elimination of infectious foci with an adequate combination of medical therapy with a conservative treatment or surgery is still valid, the advanced technology of osteosynthesis systems and prosthetic replacement for spinal, hip and knee involvement respectively, with suitable indications, affords new solutions of surgical technique. The objective is to achieve surgical procedures that preserve at best the physiology of locomotor apparatus.

Female↗

PubMedDate not supplied

The surgical treatment of spinal cord compression caused by tumorous metastases. A review of 91 cases.

Spinal cord compressions as a result of metastases are of considerable importance with regard to the quality of life and life expectancy of the cancer patient. Although surgical treatment has contributed to a considerable improvement in the life conditions of these patients, some questions still exist, particularly with regard to the choice of the time to operate. Thus, a total of 91 patients submitted to decompression were studied, taking into consideration different factors such as anatomo-radiographic findings, temporal parameters regarding occurrence of compression, and relative neurologic findings. Compression was incomplete in 44% of cases, complete in 45%, and complete with vertebral collapse in only 11%. Furthermore, it was observed that the group with partial compression included the lowest percentage of patients who resumed walking (57.5%), as compared to those with complete block (65.85%), or complete block associated with vertebral collapse (70%). This contradiction is confirmed by the observation that the resumption of walking was longer in cases with total block as compared to those with partial block. These results, apparently paradoxical ones, may be explained on the basis of the different duration of compression in the two groups. In fact, if we analyze the data relative to the interval of time between the occurrence of neurologic symptoms and surgery, we observed that patients with partial block were those in which surgical indications were made a longer period of time after the onset of symptoms. Surgical indications must be made at the first sign of deficit, regardless of the degree of compression present in the radiologic documentation, in order to avoid the transformation of reversible functional medullary changes into irreversible structural lesions.

Adolescent↗