Biomedical subjects
Publications and source records attributed to L B Greenberg.
The prospective, successful, use of ECT in a patient with a frontal meningioma is described. The authors review the literature on ECT in patients with brain tumours, and suggest factors predictive of a favourable outcome.
Dexamethasone suppression tests (DSTs) were given to nine bipolar patients in both depressed and manic phases of their illness. In seven patients DST results were consistent between episodes; six patients had positive tests in both depression and mania.
Eighteen manic patients who had abnormal results on the dexamethasone suppression test at admission were retested before discharge, when they were clinically stable. Conversion to normal suppression predicted good outcome after discharge, whereas a persistently abnormal test predicted poor outcome.
Selenium status was investigated in nine inebriated alcoholic subjects by collecting serial samples of blood and urine during hospitalization for alcohol detoxification. The selenium content of various alcoholic beverages and samples of hospital diets was also determined. Mean plasma selenium level and mean urinary excretion of selenium were both significantly lower (p less than 0.01) in alcoholic subjects as compared to the control subjects at the time of admission. Furthermore, the daily dietary intake of selenium before hospitalization was estimated to be below the recommended safe and adequate range in the majority of the alcoholic subjects. The selenium content of various alcoholic beverages was determined to be very low (0.1 to 0.8 microgram/dl). These data suggest that selenium depletion does occur in alcoholic subjects most likely due to poor dietary intake. Selenium depletion in this group of patients is corrected by cessation of ethanol ingestion and adequate dietary intake without additional selenium supplementation.
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