Biomedical subjects

L B Gutman

Publications and source records attributed to L B Gutman.

At least 19 recordsLinked to original sources

PubMed1991

[The characteristics of treating hypertension with clofelin in pregnant women].

Long-term effective use of clophelin was observed only in 1/3 of pregnant suffering of hypertensive disease. The efficacy of treatment with this drug is determined not so much by its hypotensive action as by its influence on the state of the central hemodynamics. Clophelin may often reduce the minute cardiac volume and thus, deteriorate the uterine-placental blood flow and that is why its use be carried out under meticulous control of the central circulation. The authors designed a mathematical model for the prognosis of the efficiency of long-term clophelin treatment in pregnant women with hypertensive disease.

Adult↗

PubMed1991

[The role of prostaglandins in the development of associated late pregnancy toxicosis in hypertension patients].

The plasma levels of prostaglandins A, E, and F2 alpha were measured by the radioimmunoassay in 146 hypertensive and 62 healthy pregnant females. It was ascertained that beginning in the second trimester, the ratio of various prostaglandins is impaired in the direction of increasing values of substances from the pressor group as the hypertensive disease evolves. This is due to lower levels of prostaglandins A and E and/or higher levels of prostaglandins F2 alpha. In associated late gestosis, prostaglandin levels are related to the clinical manifestations of this disease. There are increased prostaglandin F2 alpha concentrations with severe nephropathy. The studies indicate that prostaglandins affect the course of hypertensive disease in pregnant women and the development of associated late gestosis.

Dinoprost↗

PubMed1989

[Prevention of fetal and neonatal developmental disorders in diabetes mellitus].

The experience of follow-up and treatment of over 500 pregnant diabetic women and their newborns is summarised. The incidence of severe complications of pregnancy and labour is shown to rise significantly in this condition, the fetal development and neonatal status being impaired. The effects of the genetic factors, hypoxia, ketoacidosis, metabolic and hormonal errors, complicated pregnancy and labour on the perinatal disease development are defined. A comparative evaluation of various diagnostic techniques for early detection of impaired fetal and neonatal status is presented. An effective complex of organizational, therapeutic, preventive, and rehabilitation activities serve to provide for antenatal care and birth of a healthy infant in a diabetic mother.

Developmental Disabilities↗

PubMed1986