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L B Klempner

Publications and source records attributed to L B Klempner.

6 recordsLinked to original sources

Abnormally high values for direct bilirubin in the serum of newborns as measured with the DuPont aca.

To assess notably high measurements of direct bilirubin in the serum of newborns obtained on the DuPont aca analyzer, the authors compared results from the aca instrument with the results from the Technicon RA-1000 analyzer. Total and direct bilirubin values in 11 serum samples of newborn babies were measured in parallel on both instruments. There was good correspondence between the two instruments in determination of total bilirubins. However, the diazotized sulfanilic acid method (used by both instruments) yielded much higher direct bilirubin values on the aca analyzer than on the RA-1000. The possibly spuriously elevated direct bilirubin results produced by the aca may cause clinical confusion.

Bilirubin↗

Malacoplakia of the ovary.

Malacoplakia is a form of chronic granulomatous inflammation that rarely involves the female genital tract. We report a case of malacoplakia of the ovary that developed in a 50-year-old white woman with a long history of von Recklinghausen's disease and diverticulitis. In the current case, malacoplakia presented as a tumorlike lesion in the left adnexal area. It appeared grossly to invade, through direct extension, surrounding soft tissues and loops of the small and large bowels. This case simulated a malignant ovarian tumor, and presented a significant diagnostic challenge clinically and pathologically.

Female↗

[Kinetics of cell proliferation and growth of transplanted hepatoma in mice].

The authors compared the parameters of the growth and kinetics of the cell proliferation of five strains of transplantable mice hepatoma. By means of autoradiography and 3H-thymidine the curves of labeled mitoses and these of persistently labeled cells were obtained and analysed. Of all the mitotic cycle parameters: the time of G2 period and duration of phase S are mostly constant and not related with the rate of tumors growth. Hepatoma 46 is characterized by an extremely low intensity of cell production in relatively low their death rate. On the contrary, in hepatoma 48 possessing the same rate of growth the cell production was much more intensive, the rate of cell death being very high.

Animals↗

[Combined lung cancer and systemic scleroderma].

The article presents data of the literature and the author's personal two observations on combination of systemic scleroderma and cancer of the lungs. According to the data obtained, the most frequent forms of neoplasms in this combination were tumours of an adenomatous structure. A decisive role in the machanism of development of adenomatosis of the lungs was played by septo-alveolar sclerosis which led to rearrangement of the lung tissue. Potential malignancy of adenomatosis of the lungs in systemic sclerodermia was closely connected with participation of a "defective" collagen of the embryonic type in the formation of the basal membrane of the alveolar epithelium, as well as with the predominance among the tumour cells of granular pneumocytes of the B type characteristic of the embryonal period of mammals.

Adenocarcinoma↗