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L B Leybovich

Publications and source records attributed to L B Leybovich.

6 recordsLinked to original sources

Theoretical limits of SAR distributions of a four-element square array of dipole-type antennas.

Four-element dipole microwave antenna arrays with square insertion patterns are commonly used clinically for interstitial hyperthermia. One major disadvantage with this type of antenna array is the presence of a large dead length at the tips because the current gradually decreases from maximum at the junctions to zero at the tips. This dead length is usually 1.5-2 cm along the central axis of a 2 x 2 cm array of regular dipole antennas. Many attempts to improve the performance of dipole antenna arrays have been made by designing antennas with increased current at the tips. While some dipole antennas of new design show negligible dead lengths at close proximity in the single-antenna configuration, phantom experiments have demonstrated that these antennas exhibit at least 1.1 cm dead space along the central axis of the four-antenna array. Therefore, there seems to be a limit to which the array dead length can be reduced by the improvements in the dipole-type antenna design. The goal of this work is to find the theoretical minimum of the array dead length. This was done by assuming a uniform current distribution along the entire antenna. The specific absorption rate (SAR) patterns were calculated for an array with an insertion depth of 7 cm (resonant length for 915 MHz) and a variable spacing between antennas (1-3 cm). It was found that there is a dead length of 6 mm along the central axis of the 2 x 2-cm array with the uniform current distribution, which can be considered as the theoretical limit of the dead length for this array.(ABSTRACT TRUNCATED AT 250 WORDS)

Biophysical Phenomena

A practical, modular hyperthermia phantom.

A catheterized, three-component slab phantom has been fabricated for use in mapping specific absorption rate (SAR) distributions from hyperthermia applicators. A planar array of 21 closely spaced catheters, located at one surface of the 1-cm-thick slab, can be positioned at depths of 0-7 cm below the phantom surface, in 1-cm steps, through appropriate placement and orientation of this slab within the three-slab set. Owing to its modular design, the phantom can be prepared, and also purged of degraded material rapidly and without damage to the catheter tracks.

Humans

Theory and design of "shortened" multiantenna microwave applicators with controllable SAR patterns.

A "shortened" multiantenna hyperthermia applicator has been designed and tested at the Mallinckrodt Institute of Radiology at Washington University School of Medicine. By shortening the distance from antenna to aperture, an applicator is obtained that produces an SAR pattern that is essentially the same as produced by a monopole antenna. By placing several properly spaced probe antennas into the same "shortened" applicator, an applicator is obtained that produces a SAR distribution that is essentially a composite of small overlapping SAR patterns produced by weakly interacting incoherently driven antennas. Such a design significantly improves the applicator's lateral heating efficiency and allows the independent control of temperatures in certain tumor areas by changing the input power to the respective antennas.

Diathermy

SAR patterns of external 915 MHz microwave applicators.

Analysis of the results from recent clinical trials has shown that tumour size is a significant prognostic factor in eventual tumour control in patients treated with thermoradiotherapy. The critical issue appears to be the adequate coverage of hyperthermia target volume with 'therapeutic temperature'. Therefore one must choose appropriate applicators for the treatment of a given tumour. Accurate knowledge of performance characteristics of the applicators used in clinics thus becomes crucial. In an attempt to take the first step for the appropriate selection of applicators in clinics several commonly used applicators were evaluated according to their 75%, 50%, and 25% two-dimensional SAR (specific absorption rate) contours at depths of 1-3 cm. The data were subsequently approximated by rectangles. This type of information, even with its limitations, is extremely important in implementing quality assurance in hyperthermia. In this communication we will present such information, and the implications in current hyperthermia clinical trials will be discussed.

Biophysical Phenomena

Dual-antenna applicator for hyperthermia of tumours at intermediate depth.

A dual-antenna applicator with 21 x 26 cm2 aperture, that is fully loaded and operates at 74 MHz, was developed at the Mallinckrodt Institute of Radiology. By placing two antennas into an applicator capable of propagating TE10 mode, a significant enlargement of heating pattern was achieved without an increase in applicator dimensions. When antennas are placed symmetrically about a parallel to the antenna axis of symmetry, the sensitivity of the applicator input impedance to variations of load impedance reduces. Stable coupling of the RF power to the treatment area may be provided. Twenty patients with eccentrically located tumours were treated using this device.

Evaluation Studies as Topic

Evaluation of the Sigma 60 applicator for regional hyperthermia in terms of scattering parameters.

Scattering parameters adequately describe the interference between ports of a multiportal electromagnetic device when the device dimensions are comparable with the wavelength of the electromagnetic waves within the device. Since the Sigma 60 applicator is a four-port electromagnetic device, the interference between ports (quadrants) is described by a 4 x 4 scattering matrix. The load and frequency dependence of the scattering parameters were studied. The exact values of the parameters depends on the load within the applicator, but typically have minima at frequencies around 80 MHz and sometimes at 100-110 MHz. The effects of the coupling between quadrants can be substantial. Marked changes in the heating pattern can occur, particularly if the phase of the coupling element and the phase between quadrants both approach 90 degrees. Examples are shown in which the effects of coupling can qualitatively alter the intended SAR pattern. Simple steps which can be taken to minimize this phenomenon are demonstrated. Recommendations for clinical practice are discussed. Scattering parameters obtained with a non-absorbing phantom can be used for the quality assurance evaluation of the device.

Biophysical Phenomena