Topical anesthesia for bronchoscopy.
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Aged↗
Biomedical subjects
L B Perry
Publications and source records attributed to L B Perry.
Anesthesia for prolonged bronchoscopy.
At the Mayo Clinic, experience with 22 patients undergoing bronchoscopy on 29 occasions has shown that prolonged operative manipulation in the airway can be carried out safely and satisfactorily using general anesthesia. Requisites for this procedure include a period of apneic oxygenation, an adequate-sized endotracheal tube, hyperventilation of the patient during operative manipulation, and careful attention to management of postoperative bronchospasm. Prolonged bronchoscopy under general anesthesia has permitted localization of occult bronchogenic carcinoma at an earlier stage than has been possible up to this point.
Adjuvants, Anesthesia↗
Plasma dopamine-beta-hydroxylase activity and catecholamine levels in anesthetized dogs following acute hemorrhage.
Because dopamine-beta-hydroxylase (DBH) is released from storage vesicles in adrenergic nerves and the adrenal medulla along with catecholamines, determination of circulating levels of this enzyme might serve as an index of sympathoadrenal activity. This hypothesis has been studied in dogs anesthetized with cyclopropane, isoflurane, and thiopental that were subjected to a single acute hemorrhage and followed for 5 hours. Plasma DBH activity and catecholamine levels were determined before and every 30 minutes after the hemorrhage. Changes in DBH activity did not correlate well with changes in levels of circulating catecholamines in the dog in response to this form of stress.
Acute Disease↗