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Biomedical subjects

L B Warneke

Publications and source records attributed to L B Warneke.

10 recordsLinked to original sources
PubMed1993

Single photon emission computerized tomography in obsessive compulsive disorder: a preliminary study.

Patterns of cerebral perfusion in patients with obsessive compulsive disorder were evaluated using single photon emission computerized tomography. Eleven patients, who satisfied the DSM-III-R criteria and Research Diagnostic Criteria for the disorder, were evaluated using the distribution of 99m-Tc-HMPAO as a radiotracer. The Yale-Brown Obsessive Compulsive Scale was administered to each patient to assess the severity of their symptoms. The images obtained were evaluated qualitatively and semi-quantitatively by a physician in nuclear medicine who was blind to the patients' diagnoses. Eight of the 11 patients demonstrated asymmetric perfusion of the basal ganglia; the left side showed impaired perfusion in six patients.

Adolescent↗
PubMed1992

Encephalitis associated with herpes zoster: a case report and review.

This paper describes the case of a patient with a history of affective disorder who developed encephalitis associated with herpes zoster which presented as a delirium with prominent manic symptoms. Published reports of encephalitis following herpes zoster infections are reviewed. The diagnosis of herpes zoster-associated encephalitis should be suspected in individuals with changes in his or her mental state, an abnormal electroencephalogram and an abnormal cerebrospinal fluid examination which closely follow a cutaneous herpes zoster lesion.

Adult↗
PubMed1991

Benzodiazepines: abuse and new use.

Both abuse and new uses for benzodiazepines are reviewed. The pharmacology of benzodiazepines is summarized and statistics regarding their general use are given. The question of benzodiazepine abuse is reviewed in some detail and the question of rebound, recurrence of symptoms and physiological withdrawal is differentiated. Benzodiazepines are regarded as a very safe class of drugs and the abuse potential is felt to be negligible provided that they are prescribed for appropriate conditions and monitored carefully. The dangers of alternatives to benzodiazepines such as alcohol or barbiturates is emphasized. New uses for benzodiazepines are reviewed including the use of benzodiazepines in panic disorder, as well as an adjunct in the therapy of mania and some psychotic states. Rational prescribing of benzodiazepines is encouraged and the attitude that these are dangerous and addictive drugs is discouraged and put into perspective.

Anti-Anxiety Agents↗
PubMed1985

The dexamethasone suppression test in a general hospital psychiatric setting.

The use of the dexamethasone suppression test in a general hospital setting is discussed with a review of some of the literature pertaining to the test. The test was performed on a series of 47 patients where there was a high index of suspicion that depression was present. Of the patients with a final diagnosis of depression, 77% had a nonsuppressive DST. There were no false positives. Bipolar depressed patients were more likely to be nonsuppressors than unipolar patients.

Bipolar Disorder↗
PubMed1984

The use of intravenous chlorimipramine in the treatment of obsessive compulsive disorder.

Obsessional disorder has always remained a difficult illness for psychiatrists to treat with response to therapy, both psychotherapy and chemotherapy, being low. A review of the traditional approaches to the treatment of obsessional disorder is done, including a brief review of the literature on intravenous chlorimipramine. Five case histories of patients with previously non-responsive obsessional disorder are summarized. All five cases were treated in hospital with a series of infusions of intravenous chlorimipramine. The drug and route of administration was extremely well tolerated with rapid and dramatic relief of obsessional symptoms as well as improvement of mood in all cases. The theoretical action of chlorimipramine is discussed as well as possible reasons why the intravenous route appears to be superior to the oral form.

Adult↗