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Biomedical subjects

L Bódis

Publications and source records attributed to L Bódis.

17 recordsLinked to original sources
PubMed1988

[Magnesium substitution in pregnancy. A prospective, randomized double-blind study].

The results of a prospective, randomized double-blind study of magnesium substitution in pregnancy are reported. Of 997 gravidae, 985 were included in the study. Of these, 485 received magnesium aspartate (Mg 5-Longoral) and 500 a placebo. The results show that the course of pregnancy was better in the group which received the magnesium aspartate in a daily dose of 15 mmol (Mg 5-Longoral) than in the group given placebo. Among the women treated with magnesium were fewer premature births (less than 258 days' gestation). The proportion of newborns, small for date (less than 2500 g), was lower, as was the proportion of newborns with intrauterine retardation (greater than 10th percentile). There were significantly fewer cases of EPH gestosis in the magnesium group, and no serious side effects of treatment. In the authors' opinion, magnesium substitution should be included in routine antenatal care.

Aspartic Acid↗
PubMed1987

The effect of droperidol on the ST-T segment of the ECG.

It is generally accepted that droperidol as a dopaminergic blocking agent has some influence on heart function. Therefore, a study was performed to investigate the effect of droperidol on the so-called ischaemic ST-T segment depression in the ECG. Droperidol treatment 0.1 mg/kg b.w. in a single i.m. injection was performed in 30 patients 21 women and 9 men, aged 15-55 years producing marked ST-T depression in at least two conventional leads, at rest. Droperidol had a beneficial effect in the majority of patients, i.e. the ST-T segment inversion had normalized in 23%, and improved in 30%. It is concluded that droperidol abolishes the ST-T alteration produced by dopaminergic mechanism.

Adolescent↗
PubMed1986

Effects of intraamniotically administered thyroxin on acceleration of fetal pulmonary maturity in preeclamptic toxemia.

In 18 cases of serious and fairly serious toxemic pregnancy, the authors gave 500 micrograms L-Thyroxin "Henning" intraamniotically after the laboratory evaluation demonstrated negative pulmonary maturity from an amniotic fluid sample. Maternal and fetal complications due to the drug could not be observed. Despite a 39% premature incidence, IRDS and hyaline membrane disease were not observed. The administered T4 caused a positive change in the direction of the L/S ratio and the Clements test. The other amniotic fluid parameters did not change, except the T4 level. The extremely high T4 level obtained 48 hours later gradually became normal several days later. The T4 values obtained from the blood of the mother and the newborn on the 5th postnatal day were normal. In toxemic cases where the induction of labor is vital and there is a risk of IRDS and steroid application in contraindicated, intraamniotic thyroxin is recommended as prophylaxis for IRDS.

Adolescent↗
PubMed1984

Effect of metoprolol in carotid sinus hypersensitive patients.

The reflex effects induced by carotid sinus stimulation were studied in 23 subjects before and after oral administration of 200 mg metoprolol. Eight patients had sustained hypertension, eight had normal blood pressure. All patients had carotid sinus hypersensitivity (CSH). Seven normotensive subjects without carotid sinus hypersensitivity constituted the control group. Two hours after intake of metoprolol the baroreflex induced sinus node inhibition and blood pressure lowering effect proved to be greater, in all groups of subjects, than before taking the drug, however, in the group of carotid sinus hypersensitive patients with high blood pressure only the parameters relating to heart rate showed significant differences. In a comparison of the effects of the metoprolol on the parameters induced by carotid stimulation, significant increases could be seen in both CSH groups compared to the data found in the control group. The reflex induced fall in blood pressure and the time needed for the return to the prestimulating level showed a significantly greater augmentation in the normotensive, than in the hypertensive CSH patients.

Blood Pressure↗
PubMed1983

[Experiences with tocolysis].

The results of tocolysis applied for delaying premature delivery and abortion is reported as well as its side effects in the mother. 168 patients were included in the study. It is stated that fenoterol can be successfully administered for stopping early contractions. The side effects of the drug are relatively mild and avoidable. It is also stated that fenoterol treatment is not superfluous even in case of a ruptured membrane when the fetal lungs are not ripe yet. Looking for combined possibilities should be the subject of future studies.

Administration, Oral↗
PubMed1980

Effect of steroid prophylaxis and of elective caesarean section on maternal and fetal cortisol values.

The cortisol level was studied during and after delivery in the mothers and their newborns after normal deliveries, elective Caesarean sections, and steroid pre-treated vaginal deliveries. The suppressive effect of Caesarean section, and steroid pre-treated vaginal deliveries. The suppressive effect of exogenous steroid was observed in both the mother and the newborn but its extent was not significant and its duration transitory; in 48 hours it disappeared. In the newborns delivered by elective Caesarean section, an extreme increase in the cortisol level was observed. The cortisol level in the amniotic fluid was not suitable for evaluating the function of the hypophysis-adrenal axis, especially not after steroid prophylaxis.

Amniotic Fluid↗
PubMed1979

Clinical aspects of carotid sinus hyperaesthesia.

Carotid sinus hyperaesthesia (CSH) was found in 605 of the clinical cases observed by the authors in a 6-year period. In the patients with CSH, disorders of impulse formation and conduction, both at rest and in response to the carotid compression test, were prevalent. No relationship was demonstrable between the duration of carotid compression and the consequent rhythm disorders. Nor did the vascular state of the CSH patients affect the type, duration or severity of arrhythmia elicited by carotid compression. In 8 cases of CSH unilateral carotid sinus infiltration with lidocain was performed with the objective of pharmacological denervation. Predominance of sympathicotonia induced in this manner was not found to be provocative of arrhythmia. Sensitization of the carotid sinus reflex in response to i.v. administration of 0.5 mg digoxin was confirmed on the evidence of clinical investigations.The results thus obtained are primarily attributed to a decreased sympathetic efferentation.

Adolescent↗