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L Ballowitz

Publications and source records attributed to L Ballowitz.

47 records · Page 3Linked to original sources
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[Recent studies on the pathogenesis of hyperbilirubinemia and kernicterus].

After a short summary of recent studies on the blood brain barrier and bilirubin entry into the brain and the intestinal bilirubin absorption, a report is given on actual investigations in Gunn rats. The animals were given by gavage a bilirubin stock solution and simultaneously milk or different milk ingredients. Cream, oil and lipid emulsions delayed bilirubin absorption.

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Pharmacokinetic studies of the enterohepatic circulation in Gunn rats.

Pharmacokinetic investigations of bilirubin resorption by the intestine of Gunn rats have shown that the excretion of bilirubin is markedly dependent upon the frequency of defaecation. The serum bilirubin concentration is strongly affected by obstipation or diarrhea, so therefore the influence of diet upon this parameter in Gunn rats was investigated. Not only natural breast milk but also adapted milk strongly inhibited the resorption of bilirubin. This cannot be attributed to an increased defaecation frequency. Instead it is postulated that the resorption of bilirubin is hindered due to a masking effect of the fat present in the nutrient.

Animals↗