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Biomedical subjects

L Baolin

Publications and source records attributed to L Baolin.

3 recordsLinked to original sources
PubMed1994

Early histologic response to titanium implants complexed with bovine bone morphogenetic protein.

This study established a method for combining bovine bone morphogenetic protein (bBMP) with titanium and evaluated the early bone formation induced by the bBMP/titanium complex in edentulous dogs. Results showed newly formed bone within the interface bone 2 weeks after implantation and nearly complete osseointegration 4 weeks after implantation. Bone formed with the apical opening of the implant within 1 month. This study indicates that osseointegration can be enhanced by bBMP-bone induction. The apical opening of the implant may provide a site in which osteogenesis can occur with protection from implant stress before and after loading.

Animals↗
PubMed1993

The effect of bone morphogenetic protein on osseointegration of titanium implants.

This study evaluated the osteointegration of threaded cylindrical uncoated endosseous implants in combination with either bovine bone morphogenetic protein (bBMP) (group 1) or bovine serum albumin (BSA) (group 2) in edentulous dogs. Histologic observations showed that new bone formation was markedly increased by bBMP. The screw-surfaced implants in combination with bBMP exhibited apparent direct bone apposition 4 weeks postimplantation with no evidence of a connective tissue capsule. Thick fibrous connective tissue still encapsulated the control implants, although some new bone was observed slowly growing from the margins of the host bed. Eight weeks after implantation, there was an exact fit between the implant and the bone in group 1, and the surrounding bone was arranged in a regular manner. In group 2, there were still a few areas of thin fibrous tissue surrounding the implants. The results indicate that the rate of osteointegration was increased by bBMP.

Animals↗