Biomedical subjects

L Becu

Publications and source records attributed to L Becu.

14 recordsLinked to original sources

PubMed1988

Small kidney associated with primary vesicoureteral reflux in children. A pathological overhaul.

In this series two quite distinct pathological entities accounted for the small, often deformed, kidney found over a severe primary ureterovesical reflux. One of them is due to dysplastic abnormal metanephric differentiation, and the other is a segmental tubular atrophy with glomerular metamorphosis. In our material there is no evidence to support an inflammatory pathogenesis in these conditions. An abnormal excess vascularization is explained by an arteriovenous fistula present in both. Proper identification of the pathology underlying such cases will assist further studies on the natural history of these two diverse malformations.

Child↗

PubMed1984

Urinary kallikrein in hypertension secondary to hemolytic uremic syndrome: response to diuretic stimulus.

Urinary kallikrein excretion was measured in 43 children, mean age 8 years, who had the hemolytic uremic syndrome (HUS) during the first year of life. Twenty eight were normotensive and fifteen hypertensive. We found no difference in urinary kallikrein excretion between the normotensive and hypertensive groups. Twenty three of these children received a combination of 1 mg/kg/day of hydrochlorothiazide plus amiloride for ten days. 14 of these patients were normotensive and 9 hypertensive. The rate of kallikrein excretion did not change in the hypertensive children whereas normotensive children had a three fold increase following administration of the diuretic. The different behaviour of kallikrein excretion in both groups may reflect a change in the reactive capabilities of the vasodilator system in this form of hypertension.

Adolescent↗

PubMed1978

Tetralogy of Fallot with subpulmonary ventricular septal defect.

Among a total of 608 patients with tetralogy of Fallot, 35 with tetralogy and subpulmonary ventricular septal defect (VSD) have undergone intracardiac repair at the Children's Hospital, Buenos Aires. The crista supraventricular was absent in 62.9% of these patients; it was hypoplastic in 37.1%. Only 3 patients (8.6%) were severely cyanotic and required operation in infancy. The main and left and right pulmonary arteries were relatively large in all but 1 patient. Nevertheless, patch-graft enlargement across the pulmonary valve ring was necessary in 20 (57.1%). We believe that closure of the subpulmonary VSD increase the apparent severity of the pulmonary stenosis and necessitates patch-graft enlargement in patients in whom the appearance of the right ventricular outflow tract before repair would not have suggested its need.

Adolescent↗

PubMed1976