Biomedical subjects
L Belcheva
Publications and source records attributed to L Belcheva.
[Chronic aortitis and its complications].
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[Primary mediastinal localization of a neuroblastoma in a young man with leukemoid reaction].
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[Recurrent infarct in a young female diabetic].
A case with repeated myocardial infarction is reported in a 23-year old female diabetic, established at necropsy and not diagnosed while still living. The infarctions had been painless and their electrocardiographic manifestation had not been definite. Generalized atherosclerosis with coronary sclerosis was pathologoanatomically established, with no obturating thrombus in the magistral vessels. Diffuse microangiopathic changes, in myocardium including, were present. The pathogenetic possibilities, associated with the characteristics of the clinical picture were discussed.
[Microcirculation of the aorta and coronary arteries in patients who died of myocardial infarct and generalized arteriosclerosis].
The authors studied the microcirculation changes in ascending aorta and left coronary artery of the heart in 25 deceased with myocardial infarction, aged from 52 to 80, with two control groups: 20 cases with complicated atherosclerosis, aged from 54 to 80, and 4 cases--without atherosclerosis, aged 30-45. Histological and histochemical investigation methods were used. The authors found grave changes in vasa vasorum of aorta and coronary artery with the formation of arteries of "closing" type, hyperplasia of the muscular layer of the arterial and venous vessels anf fibrosis of their wall in the deceased with healed myocardial infarction and chronic coronary and cardiac insufficiency. Acute disturbance of blood microcirculation was observed in recent myocardial infarction, analogical to that in case of shock. Necrosis of the type of anemic infarctions and stratification of the wall with hemorrhages and fresh thrombosis were found in the media of aorta and coronary artery in myocardial infarction and atherosclerosis. Both necrosis and stratification are associated with the manifested endothelial proliferation, recent and organized thrombus in the small vasa vasorum and grave structural changes in the supplying vessels of aorta and coronary arteries.