[Recommendations on the structural characteristics of the intensive care unit. SIAARTI Study Group for the Safety in Anesthesia and Intensive Care].
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Biomedical subjects
Publications and source records attributed to L Bianchetti.
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The value of administering 25 mg of levosulpiride per os approximately one hour before the sodium fluorescein bolus used in fluorangiography is assessed in order to avoid to the onset of nausea and/or vomiting during and after the test. The study was performed in 35 patients. No nausea and/or vomiting was observed in over 90% of cases treated.
The efficacy of tricyclic antidepressants in association with neuroleptics having been demonstrated in patients suffering from so-called tardive post-herpetic neuralgia, 43 patients were given this treatment either alone or in association with transcutaneous nerve stimulation (TENS). Of the 33 patients given drug treatment alone, 25 found relief from pain in 3-18 months, 5 produced a partial result and in 3 the treatment failed. The results obtained suggest that this is the most effective treatment as long as it is continuous and given for at least 3-6 months. The use of TENS produced no benefit.
In normal man the sympathetic nervous system could exert an inhibitory influence on aldosterone responsiveness to angiotensin II. The possible role of alpha-1 adrenoceptors in the modulation of aldosterone response was assessed by studying the changes of plasma aldosterone during infusion of angiotensin II at the doses of 1, 2, 5 and 10 ng/kg.min or after corticotrophin injection, 0.25 mg, in 9 normal subjects before and after treatment with the selective alpha-1 adrenoceptor antagonist, prazosin. Prazosin, given during 3 weeks, did not modify supine arterial pressure, heart rate and the plasma levels of angiotensin II, renin, aldosterone or adrenaline but caused a significant (P less than 0.05) increase of plasma noradrenaline. The correlation relating plasma aldosterone to plasma angiotensin II levels before and during angiotensin II infusion and the response of plasma aldosterone to corticotrophin was not modified by prazosin. These findings suggest that in normal man there is no inhibitory influence of the noradrenergic system on aldosterone responsiveness to angiotensin II mediated by an alpha-1 dependent mechanism.
After a brief review of the most recent findings on peripheral nerve nociception and deafferentation, the advisability of considering two so-called neuralgias - postherpetic neuralgia and phantom limb pain - in the more complex framework of deafferentation syndromes is examined together with the consequent need for a basic review of the therapeutic approaches pursued up to the present in the antalgic treatment of these two syndromes.
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The results of a study of 32 patients with the clinical and auscultatory suspect of M.V.P., confirmed echo-cardiographically, are reported. Part of the pathogenetic cause of the symptomatology and ECgraphic alterations are attributed to the hypomagnesiemia. The relation between exercise test positivity and gravity of the symptomatology is confirmed. The phonomechanocardiographic tracings were studied and the morphological features from C.P. and apexcardiogram are described and shown, with particular attention given to the clicks and systolic murmurs. The authors describe three types of prolapse, early, "U"-and "double U"--shaped pansystolic, and, relating echo-to-phonomechanocardiographic results, point out features which seem typical of the M.V.P. Echo-phono mechanocardiography is confirmed as a technique which is useful and sufficiently safe and reliable in diagnosing, detecting and following the disease in its not yet perfectly acknowledged evolution. It avoids the use of invasive tools which could become extremely dangerous.
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