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Biomedical subjects

L Bloomfield

Publications and source records attributed to L Bloomfield.

2 recordsLinked to original sources

The Webb (Wb) antigen in South Wales donors.

Eight Webb antigen Wb+ propositi, 2 in the same family, were found in testing 10,117 random blood donors in South Wales with anti-Wb serum. Family studies on the new propositi confirmed the Wb antigen to be inherited as an autosomal dominant character. Wb segregated independently from ABO, Rh, MNSs, K, Fy, Jk, and was not X- or Y-borne; for the first time Wb was shown to be independent of Lu. Wb antigen was destroyed by some proteolytic enzymes and by neuraminidase. Sera from 5,144 random donors were screened with Wb+ cells resulting in detection of 2 additional anti-Wb.

Blood Group Antigens

Community-based computerized donor record systems.

Computer programs for management of donor information have been developed for the Champaign County Blood Bank, a division of the Regional Health Resource Center, Urbana, Illinois. The system provides the blood bank with reports from the donor files, incorporating the donor's last donation dates, ABO groups and Rh factors, memberships in assurance programs, and rare donor information to generate lists to meet either daily or emergency inventory needs. The system was designed to decrease time requirements for donor recruitment, improve donor base sampling, aid in support of special recruitment programs, and provide statistical profiles of the community donor base. Experiences in the development and use of the system indicate requirements for effective development of such systems include careful design, strict monitoring of performance, use of a versatile programming language, and incorporation of program modifications via staff-programmer interaction throughout implementation.

Blood Donors