[Chronic leg artery syndrome of exceptional aetiology: regarding 2 cases].
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Adult↗
Biomedical subjects
L Bonnevie
Publications and source records attributed to L Bonnevie.
[Anaesthesia and amiodarone-associated hyperthyroidism].
Amiodarone can induce severe hyperthyroidism that justifies its withdrawal and initiation of antithyroid drugs. Impossibility to stop amiodarone, failure to control hyperthyroidism and unfavourable evolution can lead to thyroidectomy. Cardiac manifestations, persistence of hyperthyroidism and interactions between amiodarone and anaesthetic or haemodynamic drugs may contraindicate anaesthesia. We report nine consecutive cases of amiodarone-associated hyperthyroidism that prompted us to perform thyroidectomy under general anaesthesia. The features and anaesthetic data of patients were noted. The antithyroid medical treatment failed in all patients. After thyroidectomy, evolution was favourable in all nine cases, without any intra or postoperative complication, in spite of the extent of hyperthyroidism and the severity of the associated cardiac problems. Despite potential high risks, thyroidectomy for amiodarone-induced hyperthyroidism does not seem to increase morbidity or mortality and allows a quick return to euthyroidism and reintroduction of amiodarone.
Adult↗
[New methods of cardiac imaging: a revolution in the management of diabetics].
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Calcinosis↗
[Importance of transesophageal echocardiography and computed tomography in the differential diagnosis of a case of papillary fibroelastoma revealed by a neurologic accident].
In the light of a new case revealed by a stroke, the authors confirm the importance of transesophagal echocardiography (TEE), and show that multislide computered tomography can be used as a new efficient tool for the diagnosis of cardiac papillary fibroelastoma (CPF). These benign tumours of endocardium are rare and case reports have been published sporadically. Stroke is an usual clinical complication and the most frequent symptom associated with CPF. Transesophageal echocardiography is the reference for diagnosis of CPF when transthoracic echocardiography is normal. When TEE is contraindicated or technically impossible, multislide computered tomography appears as an interesting alternate solution for diagnosis because of its fast acquisition and high spatial resolution. Symptomatology may be connected to either tumoral embolisation or cruoric emboli. Surgery is required for any symptomatic tumour.
Aged↗
Procedural characteristics of primary coronary angioplasty in diabetic patients with acute anterior myocardial infarction.
BACKGROUND: Mortality and morbidity rates are higher in diabetics compared to non-diabetics after acute myocardial infarction (AMI). Previous angiographic studies regarding primary angioplasty for the treatment of AMI found that angioplasty was similarly successful in diabetics and non-diabetics. However, it is noteworthy that patients of "real life" are often far from the population randomised in prospective protocols. The aim of this study was to examine the procedural characteristics of consecutive diabetic patients hospitalised for anterior AMI and treated with primary angioplasty as compared to non-diabetics. METHOD: We analysed 28 consecutive diabetics and 74 non-diabetics who underwent primary angioplasty for anterior AMI (< 12 h from the onset of symptoms) during 15 consecutive months between 2000 and 2001 in our institution, depending on the presence or absence of diabetes. RESULTS: Among analysed data, we found that in diabetics compared to non diabetics: (i) the delay before arrival in the cath-lab was significantly longer (5.5 +/- 2.7 vs 4.2 +/- 2.8 h); (ii) there was a less important collateral flow coming from the non-culprit arteries towards the culprit artery; (iii) there was a less important rate of recovery of a normal flow (TIMI 3) in the culprit artery after coronary angioplasty (67% vs 91%). CONCLUSION: Our study demonstrates that several procedural characteristics could explain the poorer prognosis of AMI treated by primary angioplasty in the diabetic population. The longer delay found in diabetics before arrival in hospital could probably be improved.
Angioplasty, Balloon, Coronary↗
[Input of coronary artery calcium score assessed by computed tomography in the screening of diabetic coronaropathy].
The poor prognosis of coronary artery disease along with the inaccuracy of available testing methods have favoured the development of new screening techniques. One such innovation involves measuring the coronary artery calcium score (CAC). Through computed tomography, this test quantifies the amount of calcium deposited in coronary arteries, itself a reflection of the degree of atherosclerosis. This investigation is a prospective study of 48 diabetic subjects comparing the performance of CAC score with the gold standard testing methods. The results of our study showed that, due to its high negative predictive value, 5 invasive tests were performed needlessly as these subjects had very low CAC scores. At this time, the CAC score is not recommended for every patient but rather on a case-by-case basis. However, it may soon emerge as the next step after the ECG in the evaluation of coronary artery disease. This would alleviate the need for more invasive tests in those patients for whom such investigations are deemed unnecessary. The CAC score, when matched for age, sex and other variables, could also serve as an indication for prescribing medications such as statins, along with other therapeutic interventions. Diabetologists, cardiologists and radiologists must work together in order to gain a better understanding of these new techniques. This may facilitate the emergence of a new approach to the treatment of coronary artery disease.
Calcium↗
Angiographic characteristics of coronary artery disease in diabetic patients compared with matched non-diabetic subjects.
The aim of this study was to assess the extent and the severity of coronary artery disease (CAD) in diabetic patients. Angiographic findings were retrospectively analysed in 50 diabetic and in 50 non-diabetic patients, matched for age and sex, undergoing coronary angiography for evaluation of clinically CAD or silent ischaemia. Baseline characteristics did not show any increase of cardiovascular risk in diabetics compared to the non-diabetic group. Diabetic patients present less chest pain and more electric abnormalities, reflecting CAD specificity for diabetic patients. Angiograms of the coronary tree were divided into 13 segments and two experienced angiographers have developed a methodic analysis of selected coronary segment stenosis. The number of significant coronary artery stenosis (> or = 50%) per patient was higher in diabetic than in non-diabetic subjects (5.06+/-2.16 vs 2.40+/-1.97, p < 0.05). Diabetics had also more left main CAD (7/50 vs 1/50,p < 0.05). Though we did not find at any time statistical difference for multivessel, distal or diffuse CAD between the two groups, nevertheless there are more diffuse and distal lesions of the diabetic coronary artery trees. This debate is not closed, there is always controversy concerning whether the angiographic findings in diabetic or non-diabetic patients are different. But these results corroborate the hypothesis of a greater severity of angiographic proven CAD in diabetic than in non-diabetic patients, especially in the left main coronary artery.
Aged↗
[Postpericardiotomy syndrome; a rare complication of transcavitary cardiac pacing: apropos of a case].
The authors report a new case of the post-pericardiotomy syndrome occurring after implantation of a DDD pacemaker. This is a rare complication of the insertion of a screw atrial electrode, the iatrogenic potential of which has already been reported. The immediate outcome was favourable with anti-inflammatory therapy.
Aged↗