Biomedical subjects

L Borisova

Publications and source records attributed to L Borisova.

5 recordsLinked to original sources

PubMed1987

[SH group content and hydrolase activity of the small intestine mucosa in chickens fed a mixture containing aflatoxin B1].

The effect of aflatoxin B1 on the content of SH-groups and the activity of leucinamino peptidase, Mg (Na+, K+), ATP, and glucoamylase in the mucous membrane of the small intestine of birds was studied. The experiment was carried out with three groups of male broilers. The controls were given starter and finisher mixtures with 21.6 and 19.5 per cent protein, with no aflatoxin B1. The birds of the test groups (II and III) were offered one and the same mixture containing 0.250 and 0.600 ppm of aflatoxin B1. By the end of the finisher period on the 49th day mucosa homogenate was used to determine the content of SH-groups and the activity of leucinamino peptidase, Mg (Na+, K+), ATP, and glucoamylase. It was found that rates of 0.600 ppm in the feed suppressed the activity of Mg (Na+, K+) ATP in the mucosa of the small intestine. Lower amounts (0.250 ppm) produced no effect on the activity of this enzyme. Leucinamino peptidase, glucoamylase, and the SH-groups did not change essentially their activity at the two rates of the toxin.

Aflatoxin B1↗

PubMed1987

[Experimentally induced aflatoxicosis in broilers].

Aflatoxicosis was induced under experimental conditions in two groups of broiler birds fed in the course of the entire fattening period upon feed, containing 0,250 and 0,600 ppm aflatoxin. Dependable changes were established in the investigated haematological and biochemical indices. There was a drop of the body weight and an increase in the feed to gain ratio. Pathologic changes were recorded in the liver.

Animal Feed↗

PubMed1985

[Paraclinical research on broiler chickens treated with aflatoxin B1 and microbiological studies of the meat and liver obtained from them].

Studied were some paraclinical indices of the blood of 50 broiler birds treated with aflatoxin B1. It was found that the effect of the mycotoxin used in concentrations of 25.0 and 37.5 micrograms in the course of thirty days and in conc. of 50.0 micrograms in the course of five days with three test groups of birds (as compared to a group of controls) consisted in the drop of total protein and the rise of the activity of GOT, GPT, and total bilirubin. It was demonstrated that the use of feeds containing aflatoxin B1 had a bearing on the microbiologic status of the meat and liver. There was no increase in the total count of aerobic mesophile organisms.

Aflatoxin B1↗

PubMed1975

[Influence of ammonia gas on indices of protein metabolism in broilers].

The effect was studied of various concentrations of ammonia (5, 20, 50 and 100 ppm) on 20-day old chicken broilers for 120 min. The birds were killed in order to study the protein content in the liver, heart musculature, and blood serum as well as the content of the free amino acids and tryptophane. Followed up was also the transaminase activity of the liver and heart musculature and the activity of GOT and GPT. It was established that ammonia does not alter the content of proteins in the investigated organs and blood serum. A dependable increase in the concentration of the free amino acids in the blood serum observed. Under the effect of 50 and 100 ppm there was no decrease in the tryptophane content of the liver and the blood serum. High concentrations of ammonia decreased the transamimase activity of the liver and heart and raised the activity of the serum GPT.

Alanine Transaminase↗

PubMed1975

[Efficacy of aerosol disinfection with lactic acid and its effect on the body of poultry].

Comparative studies were carried out to establish the efficacy of lactic acid as a disinfection means. The following pattern was observed in employing the agent: a 20 per cent conc. of the acid at the rate of 20 cu. cm per cubic meter is dispersed three times as an aerosol (at 8, 12, and 6 oclock) in the course of twenty minutes. It was found that the microbial contamination of the air drops three to four times. More pronounced is the bactericidal effect on the coliforms and moulds. The birds of the group treated with lactic acid gain 30 g more per day up to the end of the fattening period. Dependable is the higher serum level of protein as well as the higher protein content of the liver and heart musculature and of the essential amino acid tryptophane in the blood serum and liver of the test birds. Higher was also the glycogen content of the liver of the test group broilers.

Aerosols↗