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Biomedical subjects

L Borselli

Publications and source records attributed to L Borselli.

At least 19 recordsLinked to original sources
PubMed1989

Evaluation of GH secretion.

The Authors analyse the main body of somatotropin function test: insulin hypoglycemia; arginine; ornithine; I-dopa; clonidine; galanin; GH-RH; physical exercise; sleep; combined stimuli; spontaneous GH secretion of varying duration. The advantages and disadvantages of the different tests are pointed out and some recent contradictory findings concerning the newest prolonged techniques are reported. The Authors claim priority for the clinical/auxological examination, with measurement of bone age and growth velocity and suggest the procedure for GH deficit diagnosis to be followed, also in the light of their personal experience.

Animals↗
PubMed1989

[Behavior of alpha 1-acid glycoprotein in the premature infant].

The interest of clinicians has recently turned to the study of acute phase proteins whose determination, especially in the newborn, offers not only diagnostic information, but also information about prognosis. For many years we have been interested in the study of orosomucoid behaviour in newborn term babies and in low weight premature babies. For this purpose 113 patients were tested, divided into different gestational age groups, from which samples were taken immediately after birth, on the following days and before beginning any kind of treatment to show the behaviour of acid glycoprotein until normal average values were reached. Statistical processing of the data showed an average orosomucoid value in newborn term babies in perfect agreement with the literature. There was correlation among gestational age, weight at birth and orosomucoid concentration, which peaked more quickly the greater the gestational age and weight at birth. Thereafter, the concentration decreased until it stabilised at average term newborn values.

Female↗
PubMed1977

[Statistico-mathematical correlation of the B and C isoenzyme ratio of carbonic anhydrase and fetal hemoglobin, and its probable biological significance in the metabolism of zinc].

The AA. performed a study on the Bravais-Galton's correlation coefficient. They applied this coefficient to the HCAB/HCAC ratio and to the fetal haemoglobin often groups of twenty children (one month four years old) values. The result support the assumption that there is a strong biochemical relationship between zinc-carbonic anhydrase and haemoglobin in erithrocytes.

Age Factors↗
PubMed1975

["Preparative" chromatographic fractionation of human carbonic anhydrase isoenzymes. Specific studies on their identification].

The AA. describe a technique for chromatographic fractionation of the isoenzymes of carbonic anhydrase. They utilized a hydroxylapatite column, soaking the isoenzymes suspension at its top. As eluting solutions they utilized a series of phosphate buffers, pH 6,8, at increasing ionic strength. The elution, allowed the separation of three fractions which the AA. identified by spectrophotometric, electrophoretic and immunologic analysis and by atomic absorption spectrophotometry. -- Electrophoretic analysis showed that the "first fraction" eluted from the chromatographic column corresponding to the first peak, contained 8,5% of total protein, the "second chromatographic fraction", corresponding to the second electrophoretic peak contained 82,5%, whereas the "third" contained 9%. -- Nitrogen contents in the three eluted fractions showed the following values: 6,6% in the first fraction, 85,5% in the second, 8% in the third. These values are very near the ones obtained from ferogram. -- Spectrophotometric analysis revealed similar structure for the three fraction, in the range 230-300 nm of spectrum and a second peak at 400 nm for the third eluted fraction. -- The atomic spectrophotometric absorption revealed the presence of zinc in the three fractions, the amount of the element resulted almost constantly related to the nitrogen concentration in each of them.

Carbonic Anhydrases↗