The pathogenic role of the inflammatory reaction in poliomyelitis. Immunofluorescence, electron-microscopic and virological studies with type 3 poliovirus.
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Biomedical subjects
L Boulger
Publications and source records attributed to L Boulger.
[New viewpoints on the problem of the origin and pathogenetic significance of inflammatory reaction in viral infections of the CNS. Immunofluorescence, morphological and virological studies on the model of experimental poliomyelitis].
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Poliovirus crystals within the endoplasmic reticulum of endothelial and mononuclear cells in the monkey spinal cord.
The lumbar motor columns of a cynomolgus monkey that had become tetraplegic after experimental infection with a highly virulent strain of type 3 poliovirus were examined by electron microscopy. Crystalline aggregates of poliovirus occurred within the endoplasmic reticulum of endothelial cells as well as of mononuclear inflammatory cells. This finding suggests that the endoplasmic reticulum might be much more involved in poliovirus multiplication than has been previously supposed.
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[Electron microscopic observations with experimental poloimyelitis].
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