Biomedical subjects

L Bozzo

Publications and source records attributed to L Bozzo.

At least 37 records · Page 2Linked to original sources

PubMed1983

[Histomorphometric study of the effect of sodium dilantin on the gingival tissues of rats].

The density and collagen content of fibroblasts were measured in the gingiva of rats injected intraperitoneally with sodium 5,5-diphenylhydantoinate (Dilantin). An analysis using a point-counting procedure on stained histologic sections, was performed. The effect of Dilantin was studied in normal gingiva and in gingivitis provoked by a silk-ligature placed around the first lower molars. The silk ligature alone did not modify the number of fibroblasts in the gingiva, but affected the collagen content. Dilantin associated with this irritant caused not only an alteration of the collagen content but also had a statistically significant effect (p less than 0.1) on the number of fibroblasts. The results indicate an interaction of the effects of Dilantin and a gingival irritant.

Animals↗

PubMed1979

Changes of the thyroid gland and periodontal tissues of marmosets related to experimental hypothyroidism.

Adult marmosets of both sexes, weighing about 300 grams received intraperitoneal injections of 1.5 mCi of I131. Alterations in periodontal and thyroid gland tissues were determined 30, 45, 60 and 90 days after the administration, using the histological method. In the thyroid gland, degeneration and necrosis of the follicles and absence of the colloid substance with later substitution of the glandular tissue by a cicatricial fibrous tissue were observed. In the periodontium changes occurred in the alveolar bone, followed by degeneration of the periodontal ligament with areas of hyalinization from 30 days period up to the conclusion of the experiment. The cementum and the dentine were the last structures to present evidences of degeneration, showing areas of resorption only in the 60 and 90 days periods.

Alveolar Process↗

PubMed1976

Ingestion of Streptococcus mutans induces secretory immunoglobulin A and caries immunity.

Ingestion of killed cells of a highly cariogenic strain of Streptococcus mutans induced specific antibodies in both saliva and milk but not in serum of gnotobiotic rats. These antibodies were associated with the immunoglobulin A class. When infected with Streptococcus mutans, orally immunized animals developed significantly fewer carious lesions than nonimmunized infected controls.

Administration, Oral↗

PubMed1976

The effect of dexamethasone in traumatic changes of the periodontium of marmosets (Callithrix jacchus).

The systemic administration of steroid hormone (0.400 mg of Dexamethasone every 2 days), during a 28-day period in marmosets (Callithrix jacchus) produced modifications in the evolution of the experimental periodontal traumatism. The observed changes were osteoporosis and reduction of the periodontal fibers in quantity as well as a reduction of repair process, when compared to the control group that only received the action of the trauma from occlusion.

Alveolar Process↗

PubMed1976