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Biomedical subjects

L Buligescu

Publications and source records attributed to L Buligescu.

At least 37 records · Page 2Linked to original sources

Anti-polymerized albumin antibodies-a test for the evaluation of hepatic function in HBs Ag-positive subjects.

A number of 681 sera collected from hepatic patients and apparently healthy subjects (recruits and blood donors) were tested by immunodiffusion (ID) and hemagglutination (HA) for the presence of anti-polymerized albumin antibodies (AAA). AAA positivity was compared within the categories of patients and healthy subjects, grouped according to the presence of HBsAg. In most of the hepatic patients and healthy subjects both ID and HA were either positive or negative. However, in certain apparently healthy HGsAg carriers, the absence of AAA in ID was associated with high AAA titers in HA. These data point to the possibility of using AAA in order to differentiate an actually healthy HGsAg carrier from a HBsAg carrier with hepatic lesions.

Autoantibodies↗

[The cholestasis syndrome. A critical evaluation of an exploratory strategy].

The authors studied 160 cases of biliary stasis: 120 having intrahepatic cause (101 hepatic cirrhoses and 19 primitive biliary cirrhoses) and 40 extrahepatic cause (17 choledochal lithiases and 23 cancers of the pancreas head) and check up the diagnosis value of two investigation algorithms: echography, the first investigation, followed by hepatic biopsy puncture, if the intrahepatic biliary ducts are not dilated, or transhepatic cutaneous cholangiography if the intrahepatic biliary ducts are dilated in comparison with intravenous cholangiography in the first investigation. Echography has an increased diagnosis yield (96% sensitivity, 99% specificity), is cheap, noninvasive and is the first imaging exploration used in biliary stasis syndrome.

Adult↗

[The dumping syndrome: its risk factors and evolution].

The paper reports on a comparative study of 24 cases of operated gastroduodenal ulcer, in which the dumping syndrome appeared at a short interval after the operation, and of a control lot of patients operated for ulcerous disease without complications. This study shows that the incidence of the dumping syndrome in the ulcerous patients operated is of 12.83%, predominant in gastric ulcer (15%). Among the factors favouring the development of the dumping syndrome, mention is made of subtotal gastric resection with Billroth II anastomoses, early surgical indication, and pre-existing neuroendocrine disturbances. Although the dumping syndrome causes weight loss, its evolution in time is benign and improving after 3 years, surveillance.

Age Factors↗

[Acute alcoholic hepatitis].

In a group of 1,025 cases of alcoholic liver the authors detected 28 cases (2.73%) of acute alcoholic hepatitis on the basis of the morphologic examination, 75% were males, mean age 45 +/- 18 years. The mean amount of alcohol consumed daily was 106.7 g for a mean duration of 19.78 years. The hepatic lesional substrate was hepatic steatosis and cirrhosis in 7 cases (25%) and steatofibrosis in the other 14 cases (50%). The triggering factors were the abuse of alcohol in 27 cases and a pneumonia in the last case. The disease was characterized by fever, encephalopathy, hepatomegaly, hepatocytolytic-cholestatic syndrome. The evolution was dictated by the gravity of the background hepatic lesional substrate.

Acute Disease↗