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Biomedical subjects

L C Lassen

Publications and source records attributed to L C Lassen.

10 recordsLinked to original sources
PubMed1992

Peer comparison feedback to achieve rational and economical drug therapy in general practice: a controlled intervention study.

The aim of the study was to describe and evaluate a controlled intervention to achieve more rational and economical drug therapy in general practice. The strategy was based on peer comparison feedback and encouragement of local peer group discussions. Seven districts comprising 53, and 6 districts comprising 55 eligible practices constituted the intervention and control groups respectively. The process was evaluated by questionnaires to the GPs. 88% found the feedback diagrams relevant, and 74% expressed a wish for information about prescribing of particular drugs. The outcome evaluation was based on computerized registration of prescriptions. During the study period of 6 months the median costs per prescription increased significantly in the control group, whereas there was no statistically significant change in the intervention group. There were no significant effects on the prescribed amounts.

Cost Control↗
PubMed1991

Connections between the quality of consultations and patient compliance in general practice.

The aim of the study was to generate and test a theory about connections between the quality of consultations and patient compliance in general practice. The theory was empirically based on patient interviews in order to understand the patient's perceptions and behaviour, and on development of a list for mapping of consultations, which in turn allowed coherent descriptions of consultations and compliance. The theory suggests and explains that compliance is connected with the fulfillment of six relatively simple criteria for the quality of consultations. The theory was tested by comparing predictions of compliance derived from analyses of 63 consultations with patient questionnaire based measurements of compliance. The difference between proportions of patients who were complaint after consultations fulfilling and not fulfilling respectively the criteria was 44%. The 95% confidence limits of this difference were 21% and 67%.

Family Practice↗
PubMed1990

HIV infections and AIDS in Danish general practice--the role of the GP in AIDS prevention.

The occurrence and geographical distribution of HIV infections and AIDS (HIV/AIDS) in Danish general practice were examined in a questionnaire study sent to a 10% random sample of the GPs. Response rate was 92%. In 1988, a total of 2969 patients were tested, median 10 patients per GP. GPs had 148 HIV-positive patients (66 in Greater Copenhagen) and 60 AIDS patients (27 in Greater Copenhagen). In Greater Copenhagen 37% of the GPs had neither HIV nor AIDS patients, vs. 71% in the rest of the country. Instruction in infection prophylaxis was usually initiated by the GPs, while HIV testing was mainly on the patient's initiative. 52% of GPs indicated a change in their routine, particularly with respect to sterilization of instruments and avoidance of direct contact with blood. An extrapolation of the results of this study indicates that about 1,500 of the estimated 2,000 HIV positive patients in Denmark are known by general practitioners.

Acquired Immunodeficiency Syndrome↗
PubMed1989

Integrated health work with 'the new family'.

In this Copenhagen practice couples receive antenatal and postnatal care in group sessions. The health care professionals believe they provide a better service. Parents learn from shared experiences and benefit from the social network that is established.

Child, Preschool↗
PubMed1989

Patient compliance in general practice.

The article is a short summary of a PhD-thesis, which was accepted by the Faculty of Medicine, University of Copenhagen, May 1989. The thesis is written in Danish with an English summary. It can be obtained free at the Department of General Practice, University of Copenhagen, Juliane Maries Vej 18, DK-2100 København O, Denmark, as long as issues are still available.

Family Practice↗
PubMed1989

Medical students experience early patient contact in general practice. A description and evaluation of a new course in the medical curriculum.

In the first year of the medical curriculum at the University of Copenhagen, a new discipline has been introduced, in which general practice has the key position in providing experiences of early patient contact to the students. The course consists of three principal elements: student-patient contacts in the patient's home; lessons with the general practitioner; and lessons at the Institute of General Practice. The compulsory course is completed by a student's report, and the first course has been evaluated by qualitative analysis of these reports and by questionnaires to the students and GPs. The results indicate that it is possible to provide considerable improvement of the medical education as regards communication skills and understanding of the patients' perceptions, by letting the student establish contact with a patient in the very beginning of the curriculum. General practice provides an appropriate setting for this education for both teachers and patients.

Curriculum↗
PubMed1984

Immunohistochemical evidence for intracellular localization of plasma proteins in CNS and some neural crest derivatives in human embryos.

Recent work has provided immunohistochemical evidence for an intracellular localization of some plasma proteins in the central nervous system of chick embryos and of rat, mouse, sheep, monkey and human fetuses. A regional distribution of plasma proteins in human embryonic brain, spinal cord and some neural crest derivates is shown in this study. Alphafetoprotein was the most widespread and prominent of the plasma proteins examined in early embryos. It was observed intracellularly in the ventricular zone of the fore-, mid- and hindbrain whereas other CNS regions and neural crest derivates were negative in the earliest 9 mm crown rump length (CRL) embryo examined. The embryonic nervous system was markedly negative for all other plasma proteins tested at this stage. By 15 and 16 mm CRL, a few cells in the ventricular zone and in sensory cranial nerve ganglia were positive for albumin and transferrin whereas AFP exhibited a distribution similar to that of the 9 mm embryo. By 20 to 35 mm CRI, albumin and AFP had the same extensive distribution in the CNS. Many cells in sensory and autonomic ganglia showed positive staining for albumin in contrast to a few scattered cells which exhibited reactivity for AFP, transferrin and prealbumin. The staining pattern for albumin in the ganglia may reflect a rostral-caudal gradient in development. The possible origin of intracellular plasma proteins in the developing nervous system is discussed.

Blood Proteins↗