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Biomedical subjects

L C Maas

Publications and source records attributed to L C Maas.

17 recordsLinked to original sources
PubMed1985

24-hour ambulatory manometry in diagnosis of esophageal motor disorders causing chest pain.

The clinical diagnosis of motor disorders of the esophagus leading to chest pain usually lacks documentation by manometry despite the use of sophisticated equipment as well as pharmacologic manipulation. We have developed an ambulatory manometry system that allows us to monitor motility in the esophagus on an outpatient basis for 24 hours. This method seems well tolerated, and tracings obtained are of excellent quality, allowing careful inspection and evaluation of details. Simultaneous 24-hour esophageal pH and surface ECG recordings were also obtained. We believe the technique, when perfected, will significantly enhance the understanding and documentation of the cause of chest pain in patients with motor dysfunction of the esophagus.

Ambulatory Care↗
PubMed1981

Barrett's esophagus and active duodenal ulcer: an important clinical association.

A retrospective review of five patients with Barrett's esophagus revealed three with an associated active duodenal ulcer. Two patients also had adrenocarcinoma of the esophagus. Any patient with prolonged gastroesophageal reflux should have careful radiologic and endoscopic evaluation of the entire upper gastrointestinal tract.

Adenocarcinoma↗
PubMed1978

Sigmoid stricture: an unusual presentation of perforated appendicitis with abscess formation.

Appendicitis is the most common acute surgical condition affecting the abdomen. The manner of onset and location of pain depend, to a great extent, upon the different anatomical positions of the appendix and its proximity to the parietal peritoneum which senses the location of the inflammatory process. When perforation occurs, abscess formation or diffuse peritonitis may develop. We wish to report an unusually rare case of perforated appendicitis with abscess formation presenting clinically and radiologically as a sigmoid stricture.

Abscess↗
PubMed1977

Successful oral anticoagulant therapy in a patient with short bowel syndrome.

The case of a 41-year-old male with a history of multiple emboli and short bowel syndrome who was successfully anticoagulated with sodium warfarin is described. The prothrombin times were stabilized in a therapeutic range with warfarin doses of 5.0 mg -7.5 mg daily. The pharmacokinetics of warfarin suggests that absorption is high in the proximal intestine. The successful use of sodium warfarin in the patient substantiates this finding and demonstrates that short bowel does not necessarily preclude the use of warfarin for anticoagulation. It is suggested that patients with short bowel syndrome may be successfully anticoagulated with oral products; however, careful monitoring of each patient's prothrombin time is necessary because of the variability and extent of bowel loss.

Adult↗
PubMedDate not supplied

Myocardial tissue characterization by autocorrelation of two-dimensional ultrasonic backscatter.

To evaluate a novel method for determining the spatial distribution of echocardiographic information based on the two-dimensional autocorrelation function, echocardiographic images were obtained from specific regions of interest from 10 healthy volunteers, seven patients with genetically defined hypertrophic cardiomyopathy, and nine patients with pressure-overload hypertrophy. The wavelength of distinct peaks from the two-dimensional autocorrelation of the images was compared between groups of patients and demonstrated a significant decrease in the mean length scale associated with distinct secondary correlation peaks in patients with hypertrophic cardiomyopathy or pressure-overload hypertrophy compared with healthy volunteers (p = 0.0009). With a discriminating wavelength of 3.3 mm, the sensitivity of this technique for detecting abnormal myocardium was 84% with a specificity of 89%. This study suggests that ultrasonic tissue characterization based on the two-dimensional autocorrelation function may have potential for distinguishing normal from abnormal myocardium and provides a rationale for textural approaches to ultrasonic tissue characterization.

Cardiomyopathy, Hypertrophic↗