Biomedical subjects

L C See

Publications and source records attributed to L C See.

41 records · Page 3Linked to original sources

PubMed1992

Agreement between maternal interview- and medical record-based gestational age.

Agreement between maternal interview- and medical record-based gestational age was assessed by using data from a case-control study of childhood strabismus. The sample consisted of 383 cases of strabismus and their age-matched controls, diagnosed between 1985 and 1986 in Baltimore, Maryland, who were under age 7 years when diagnosed. Medical record-based gestational age was derived, in order of priority, from early ultrasound examination, time from the last menstrual period, pediatric examination, and obstetric examination. The intraclass correlation coefficient, kappa, and mean difference were used to compare agreement between maternal interview- and medical record-based gestational age by maternal and pregnancy characteristics and characteristics related to study design. Overall, 86 percent of mothers were within 2 weeks of the gestational age reported in the medical record. The intraclass correlation coefficient comparing maternal and medical record-based gestational age was 0.83 (95% confidence interval 0.80-0.86). Agreement was positively associated with shorter length of recall, low birth order, and having a neonatal illness related to prematurity. Agreement was poor among mothers of healthy preterm infants. There was a weak positive association between recall and some sociodemographic covariates. There was greater misclassification of prematurity in the controls than in the cases. The results suggest that, in general, women recall gestational age well, which supports the use of gestational age derived from maternal interviews.

Baltimore↗

PubMed1992

Ocular trauma in the United States. Eye injuries resulting in hospitalization, 1984 through 1987.

The discharge rate for ocular trauma resulting in hospitalization and variations in rates between US census subdivisions were examined by using hospital discharge abstracts from the 1984 through 1987 National Hospital Discharge Surveys. The average annual rate of hospitalization with a principal diagnosis of ocular trauma was 13.2 per 100,000. The rate for any ocular trauma (principal or secondary diagnosis) was 29.1 per 100,000. Males were three times more likely to be hospitalized for a principal diagnosis of ocular trauma than females. Age-specific rates for principal and secondary diagnoses of ocular trauma were distributed bimodally, with the highest peak in adolescents and young adults, and another peak among those 75 years or older. This study has begun the first step in profiling ocular trauma resulting in hospitalization in the United States.

Adolescent↗

PubMed1992

N-estimation from retrospectively ascertained events with applications to AIDS.

It is a common sampling scheme in retrospective studies that the data set includes only individuals who satisfy a certain sampling criterion. In this paper we consider the situation when the sampling criterion is a specified event, and assume that an earlier event can be retrospectively identified given the occurrence of the specified event. A semiparametric method, which is a compromise between nonparametric and parametric methods, is employed for the estimation of the expected number of the specified events (namely, the N-estimation) occurring in arbitrarily given intervals. A number of statistical properties of the estimates are developed. Due to the limitation of semiparametric models, our estimates should be regarded as conservative estimates since in general they underestimate the actual number of the specified events. This type of limitation, however, cannot be avoided with nonparametric or semiparametric models. Applications to acquired immunodeficiency syndrome (AIDS) cases are considered. The blood transfusion AIDS cases reported to the Centers for Disease Control are analyzed in detail.

Acquired Immunodeficiency Syndrome↗

PubMed1989

Statistical methods for monitoring the AIDS epidemic.

This article describes statistical methods for monitoring the epidemic of the acquired immunodeficiency syndrome (AIDS). A log-linear model is proposed to estimate AIDS incidence and its growth rate while taking account of delays in case reporting. An empirical Bayes approach for estimating the epidemic growth rate in low prevalence subgroups is introduced. These methods are illustrated with an analysis of AIDS incidence trends for seven risk groups in each of six geographic regions using the Centers for Disease Control AIDS case registry data as of September 1987. The analysis finds that AIDS incidence is currently doubling about once every two years and that the relative composition of new cases is shifting away from the older epidemics such as in north-eastern homosexual communities.

Acquired Immunodeficiency Syndrome↗

PubMedDate not supplied

Prevalence of pediatric systemic lupus erythematosus and juvenile chronic arthritis in a Chinese population: a nation-wide prospective population-based study in Taiwan.

OBJECTIVE: To estimate the national prevalence of systemic lupus erythematosus (SLE) and juvenile chronic arthritis (JCA) in Chinese children in Taiwan. METHODS: A nationwide prospective population based epidemiologic study for the prevalence of pediatric SLE and JCA was undertaken in Taiwan (23 million inhabitants). The population at risk was identified as children under the age of 16 living in Taiwan (5.78 million). All citizens have been obligated to participate in Taiwan's National Health Insurance program since 1995. This gave us access to nationwide case data from the Major Illness/Injury registry and enabled us to calculate population prevalence. The population data were derived from the 1999 Taiwan census. RESULTS: Three hundred sixty-five and 218 prevalent cases of pediatric SLE and JCA were identified, respectively. The prevalence of pediatric SLE was 6.3 per 100,000 (95% CI: 5.7-7.0). The prevalence in girls (11.2 per 100,000, 95% CI: 10.0-12.5) was 6.2 times higher than that in boys (1.8 per 100,000, 95% CI: 1.4-2.4). The prevalence of SLE substantially increased in children over the age of seven, especially in girls. The prevalence of JCA was 3.8 per 100,000 (95% CI: 3.3-4.3). The figures were similar for boys (3.5 per 100,000, 95% CI: 2.9-4.2) and girls (4.1 per 100,000, 95% CI: 3.3-4.9). CONCLUSION: In this first population based epidemiologic survey of pediatric SLE and JCA in Taiwan, we provided a good starting point in our understanding of the epidemiology of these serious conditions in the Chinese population. The discrepancies between our prevalence figures and those reported from Western countries are possibly the results from true differences pertaining to ethnicity, geography or both. Future studies are necessary to elucidate the implications suggested by these data.

Adolescent↗