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Biomedical subjects

L C Vincent

Publications and source records attributed to L C Vincent.

4 recordsLinked to original sources

Neuropsychological assessment of developmental learning disabilities in adults.

Neuropsychology has a relatively brief history in the assessment of developmental learning disabilities (DLD) in adults. For a discipline that conceptualizes clinical assessment on the basis of neurologic understanding, DLD continues to be a challenge, even today because its neurology remains relatively unknown. Nonetheless, there have been important advances in understanding the underlying brain differences in this population as well as the advancement of theory-driven models for assessment. In the context of this body of information, neuropsychological assessment provides a comprehensive means of diagnosing DLD in adults. This article describes components of a specialized neuropsychological protocol developed to diagnose DLD in adults.

Achievement↗

Memory impairment and depression in patients with Lyme encephalopathy: comparison with fibromyalgia and nonpsychotically depressed patients.

Lyme encephalopathy, primarily manifested by disturbances in memory, mood, and sleep, is a common late neurologic manifestation of Lyme disease. We compared 20 patients with Lyme encephalopathy with 11 fibromyalgia patients and 11 nonpsychotically depressed patients using the California Verbal Learning Test, Wechsler Memory Scale, Rey-Osterrieth Complex Figure Test, Minnesota Multiphasic Personality Inventory (MMPI), and Beck Depression Inventory. Compared with patients with fibromyalgia or depression, the Lyme encephalopathy group showed mild, but statistically significant, memory deficits on two of the three memory tests. In contrast, the patients with fibromyalgia scored significantly higher than both other groups on the MMPI scale most sensitive to somatic concerns (scale 1), while the depressed patients scored higher than the Lyme patients on the scales most sensitive to depression (scale 2) and anxiety (scale 7). Physical complaints and depression were not major factors in memory performance among Lyme patients. These data support the hypothesis that Lyme encephalopathy is caused by CNS dysfunction and cannot be explained as a psychological response to chronic illness.

Adult↗