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L Cöplü

Publications and source records attributed to L Cöplü.

25 records · Page 2Linked to original sources

Malignant pleural mesothelioma due to environmental mineral fiber exposure in Turkey. Analysis of 135 cases.

We reviewed data from 135 patients with environment-associated malignant pleural mesothelioma (MPM) from the Central Anatolian region of Turkey. The most significant factors suggesting the diagnosis of MPM were the village where the patient resided and the typical presenting symptoms and signs of unilateral exudative pleural effusion associated with nonpleuritic chest pain. Computed tomography and ultrasonography were very useful for evaluating the extension of the tumor in the thoracic and abdominal cavities and chest wall. The tissue diagnosis was established by either thoracoscopy (39 percent) or pleural biopsy (39 percent) in the majority of the cases. The median survival after diagnosis was 13.52 months for erionite-associated MPM and 21.56 months for asbestos-associated MPM. The actuarial survival curves for the fibrous minerals were significantly different for survival computed both from onset of the symptoms and after diagnosis. Medical or surgical treatment or both did not change the outcome of the disease.

Actuarial Analysis↗

Prevalence of asthma and allergic diseases in Turkish university students in Ankara.

An epidemiological study was performed in the students of Hacettepe University from various parts of Turkey to find the prevalence of asthma and allergic diseases and search for geographical differences in Turkey. A questionnaire related with symptoms of asthma and allergic diseases was distributed to 4600 students and filled by 4331 students (1884 males, 43.5%-2447 females, 56.5%). Periodic prevalence of asthma or allergic disease during the last 12 months was 13.5%. The prevalence of awakening with chest tightness and/or feeling of retrosternal pressure in the last month was 2%. The current prevalences of the seasonal and perennial rhinoconjunctivitis, flexural eczema, food and drug intolerances, pollen and pet animal hypersensitivities were 6.4%, 1.6%, 0.8%, 4.5%, 3%, 5.2%, and 1% respectively. Drug, food, and pollen hypersensitivities were distinctively more common in the females, whereas wheezing was more common in males. Wheezing, wheezing associated shortness of breath, nocturnal asthma for the last 1 and 12 months were more common in the students from eastern region than those from western region. The highest asthmatic attack rate was reported in the eastern region. Seasonal rhinitis and pollen allergy were more prevalent in central region than northern region. No significant geographical difference was observed regarding the drug and pet hypersensitivities. Our study has shown the importance of asthma and allergic diseases as a public health problem. Explanation of the observed geographical differences aware for further studies.

Adolescent↗