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Biomedical subjects

L Caplan

Publications and source records attributed to L Caplan.

15 recordsLinked to original sources
PubMed1992

Critical carotid and vertebral arterial occlusive disease and cough syncope.

BACKGROUND AND PURPOSE: Cough syncope typically occurs in patients with known chronic lung disease. The mechanism usually involves a combination of decreased venous return, increased cerebrospinal fluid pressure, and secondary hypocapnia, all resulting in cerebral arterial vasoconstriction. Cough syncope has not in the past been associated with occlusive cerebrovascular disease. CASE DESCRIPTION: We describe a 50-year-old man with a 6-month history of episodes of loss of consciousness during paroxysms of coughing. Physical examination showed asymmetrical upper extremity blood pressures and carotid and subclavian artery bruits. Pulmonary function studies were normal. Ultrasound and angiography showed total occlusion of the left common carotid artery, right internal carotid artery, and right vertebral artery; tight stenosis of the right subclavian artery; and a hypoplastic left vertebral artery. The patient had a left subclavian-to-left common carotid artery bypass and has had no syncope since that time. CONCLUSIONS: To our knowledge, this is the first reported case of cough syncope and severe cerebrovascular disease in which surgery led to amelioration of symptoms. Cerebrovascular occlusive disease may contribute to cough syncope.

Aortography↗
PubMed1991

The effect of excessive add power on the acceptance of progressive addition lenses.

Twenty-nine subjects wearing Varilux Plus (Varilux 2) or Varilux Infinity lenses were drawn from the UAB School of Optometry primary care clinic population. Using a double-masked, randomized cross-over design, subjects wore one pair of progressive addition lenses (PALs) with a normal add and one pair with the add overplussed by 0.50 D. Subjects wore each pair of lenses for 1 week. Twenty-five of the 29 patients preferred the normal add over the overplussed add. In all subjective response categories the normal add was rated higher than the overplussed add.

Adult↗
PubMed1987

Clinical evaluation of a custom toric hydrogel contact lens.

Eleven astigmatic patients seen in a private practice were fit with the Hydron-T custom toric soft lens. The fitting mechanics are described along with the results which illustrate the potential utilization of this lens in the management of patients with high astigmatic errors.

Adult↗
PubMed1979

Cerebral embolic disease: a complication of carotid aneurysms.

Thrombus formation in large aneurysms is well recognized. However, thrombi in small aneurysms with subsequent embolization into intracranial vessels is infrequently identified or suspected. A series of cases in which this phenomenon has occurred is documented. Since many of these examples present embolic disease without suspicion of aneurysm, definitive diagnosis can only be accomplished by angiography. The importance of this study should be emphasized since embolic disease is usually assessed only by computed tomography which fails to delineate the embolic source.

Adult↗
PubMed1979

Disease of the carotid system.

Tremendous progress has been made in the investigation of occlusive disease of the internal carotid artery. With the advent of technologic advances such as CT scanning and more highly skilled personnel for the safe performance of cerebral angiography, diagnostic capabilities have been heightened. Carotid endarterectomy and surgical shunts have expanded the surgical armamentarium. Medical treatments have also proliferated.

Arterial Occlusive Diseases↗
PubMed1979

Chronic vascular dementia.

Vascular disease is responsible for only a minority of cases of chronic dementia. Vascular dementia can be an end stage of a variety of mechansisms. Correct identification of the cause of the vascular disease is the key to successful treatment.

Adult↗
PubMed1976

Vasculitis with urticaria, hypocomplementemia, and multiple system involvement.

A patient with cutaneous necrotizing vasculitis had chronic urticaria associated with multiple system involvement including arthralgias, glomerulonephritis, myositis, pseudotumor cerebri, and adenopathy. Persistent hypocomplementemia is noted with classic pathway activation. The syndrome recognized in this patient and those few individuals reported previously seems to constitute a distinct category of collagen-vascular disease.

Adult↗