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Biomedical subjects

L Carter

Publications and source records attributed to L Carter.

At least 91 records · Page 5Linked to original sources
PubMed1980

A simplified intrapartum numerical scoring system. The prediction of high risk in labor.

An analysis of 1,994 consecutive parturient women showed that 472 (23%) could be assigned to a high-risk category on the basis of an intrapartum score of greater than or equal to 3. Perinatal mortality, neonatal morbidity, and the rate for operative intervention were all significantly greater for the high-risk group (p < 0.0001). Of the total population, 11% were designated to be at high risk by combining intrapartum and antepartum scores, and 71% of this group had an abnormal intrapartum outcome (p < 0.0001). For this study, 63% of the patients with an abnormal outcome for labor were admitted to the labor floor for 6 hours or longer, and this is an indirect measurement of the potential that exists for optional management. The limitations of intrapartum scoring systems are discussed, particularly with respect to their design, the prediction of preventable deaths, and the category of hospital for which they might prove most useful.

Female↗
PubMed1979

Erythrocytes: a new cell type for the evaluation of insulin receptor defects in diabetic humans.

Human erythrocytes have specific insulin receptors. When studied in an insulin radioreceptor assay, erythrocytes from adult-onset, nonobese diabetic subjects bound at least 42 percent less insulin than the normal subjects at insulin concentrations from 0.1 to 100 nanograms per milliliter. The diabetic subjects had 190 insulin receptor sites per cell as compared with the 380 insulin receptor sites per cell for the normal subjects. The deficit of insulin binding in the diabetic subject was thus associated with a fewer number of insulin binding sites per cell with little or no change in affinity. The erythrocyte is a readily available cell for the evaluation of cellular insulin receptor activity.

Adult↗
PubMedDate not supplied

Preoperative visiting: a role for theatre nurses.

Over the past 20 years, giving preoperative information to patients has been recognized as benefiting them greatly (Hayward, 1975; Boore, 1978). Similarly, preoperative visits by theatre nurses have been widely advocated to allay patient anxiety. This article discusses preoperative visiting from the perspective of its value to theatre nurses, particularly in the planning of patients' nursing care and in the application of nursing models and a team approach to the delivery of care. In so doing, preoperative visiting may be a life-line for theatre nurses at a time when their unique contribution within the operating theatre is increasingly under scrutiny (Bevan, 1989).

Anxiety↗
PubMedDate not supplied

Liquid chromatographic preparative method for isolating ergot alkaloids, using a particle-loaded membrane extracting disk.

A liquid chromatographic method is described for the determination of ergot alkaloids in wheat. Ergonovine, ergotamine, ergocornine, alpha-ergocryptine, and ergocristine are extracted from wheat with methanol-0.25% concentrated H3PO4 (40 + 60) pH 2.2, cleaned up by using a solid-phase extraction (SPE) disk, and separated by reversed-phase liquid chromatography with fluorescence detection. Ergot alkaloids are basic compounds that form water-soluble salts in acidic aqueous solution. Because ergot alkaloid salts are positively charged, they can be easily and selectively trapped on a negatively charged strong cation-exchange SPE disk. A strong wash solvent, methanol-0.25% concentrated H3PO4 (40 + 60) was used to remove matrix interferences not bonded by ionic interactions with the cation-exchange column. The ergot alkaloids were eluted from the ion-exchange column by adjusting the pH of the elution solvents to slightly basic conditions (pH 9). The SPE disk concentrated and cleanly separated the ergot alkaloids from matrix interferences. Standard calibration curves for ergot alkaloids for the concentration range 0.1-2.0 microg/mL were linear. The SPE disk had a column capacity equivalent to about 1 g extracted wheat. At spiking levels of 2.3-46 ng/g for ergonovine and 20-400 ng/g for ergotamine, ergocornine, alpha-ergocryptine, and ergocristine, the mean recovery was 88.1% with a coefficient of variation (CV) of 5.33%. The recovery data ranged from 79.1 to 95.9%. Ergonovine had the lowest overall recovery and the largest CV. The method has an estimated reliable limit of detection and limit of quantitation of <5 and <20 ng/g, respectively, for each ergot alkaloid tested.

Chromatography, Liquid↗
PubMedDate not supplied

Limited survey of deoxynivalenol in wheat and corn in the United States.

A limited survey was conducted over a 2-year period to determine the incidence and levels of deoxynivalenol (DON) in corn and wheat grown in selected areas of the United States. Samples of corn (198) and wheat (247) were collected and analyzed by a gas chromatographic method. Sixty-six percent of the corn samples collected in 1984 and 30% of the corn samples collected in 1985 contained DON. The average concentration of DON in corn, by state, ranged from 0.11 to 1.20 micrograms/g; the maximum concentration was 2.47 micrograms/g. Only 2 of the 247 samples of wheat contained DON at a concentration greater than 2 micrograms/g, which is the level of concern suggested by the Food and Drug Administration for wheat entering the milling process for human consumption.

Sesquiterpenes↗