[Vasculitis linked to biotin use].
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Biomedical subjects
Publications and source records attributed to L Cascante.
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We have analyzed the clinical, analytical, radiologic, therapeutic an evolutive of cases of systemic mastocytosis (SM) skin lesions. The diagnostic of MS is difficult in the absence of skin lesions.
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BACKGROUND: The ISAAC (International Study of Asthma and Allergies in Childhood) was thought in order to maximize the value of epidemiological research into asthma and allergic diseases in childhood, establishing a standardized methodology and facilitating collaboration and comparison between several countries. METHODS AND RESULTS: The written questionnaires in the group of children aged 6-7 years was answered by the parents and the group of children aged 13-14 years self-completed the written questionnaires. RESULTS: 3,040 children aged 13-14 years answered the questionnaire and 3,002 in the group aged 6-7 years. In the group of children aged 13-14, 49.7% referred rhinitis symptoms some time, and 15.6% in the 6-7 year old group. The prevalence of nasal symptoms in the last year was 35.5% in the 13-14 year group and 10.6% in the 6-7 year group. The presence of nasal symptoms was more frequent in winter. The prevalence of seasonal allergic rhinitis (hay fever) was 6.1% in the 13-14 year group and 4.8% in the group of children aged 6-7 years. CONCLUSIONS: These results can contribute to a better control of some factors and to future studies where the etiology and incidence of the disease could be investigated.
The clinical and pathological findings in five patients with dermatomyositis are described. The diagnostic value of the cutaneous lesions in the disease, indicating the histological patterns of each cutaneous sign is stressed. Based in our experience and in the reviewed literature, we consider that Gottron's papules and poikilodermatomyositis present histological aspects that allow us to confirm the diagnosis suspected by clinical findings. Likewise we review some special difficult aspects of the disease such as infantile forms, association with neoplasias and overlap syndromes.