Retinal involvement has been documented in a number of patients with pigment dispersion syndrome, which also appears to be associated with a higher than normal risk of retinal detachment. We studied 24 patients with this syndrome to determine the prevalence of lattice degeneration and other retinal disorders associated with a predisposition to detachment. Lattice degeneration was found in 8 of 24 patients examined, with a prevalence that is significantly higher than that reported for normal subjects. Four eyes presented areas of retinoschisis and only one displayed a rhegmatogenous detachment. A father and son (both myopes) were found to have similar lattice lesions in the same retinal quadrants. These findings suggest that pigment dispersion syndrome may be associated with developmental anomalies that are not restricted to the anterior chamber but involve other portions of the bulb as well.

Adolescent↗

PubMedDate not supplied

Indocyanine green dye-enhanced micropulsed diode laser: a novel approach to subthreshold RPE treatment in a case of central serous chorioretinopathy.

PURPOSE: To present a case of central serous chorioretinopathy (CSC) treated with indocyanine green (ICG) dye-enhanced subthreshold micropulsed diode laser photocoagulation. METHODS CASE REPORT: A 35-year-old man presenting with recurrent CSC with persistent serous detachment of the sensory retina in his left eye who declined treatment with a 532 nm laser. Subthreshold treatment, with no visible endpoint, was performed with an 810 nm diode laser 15 minutes after the injection of 25 mg ICG in 2 cc of 5% glucose solution. The laser energy was delivered over the active leakage sites with a sequence of repeated 500 ms "envelopes" each containing a train of 250 micropulses with 500 mW peak power at 10% duty cycle (200 micros ON and 1,800 micros OFF) and each separated by 500 ms intra-envelopes relaxation time. Due to the absence of visible laser-induced lesions, post treatment ICG digital angiographic images were taken without further dye injection to verify that the hypofluorescent spots resulting from the subthreshold laser applications coincided with the points of leakage. RESULTS: After 7 days, the patient presented with a less hyperopic refraction, improved visual acuity, and reduction of serous neuroepithelial detachment. No signs of laser treatment were visible at fluorescein angiography. After 8 weeks, the serous neuroepithelial detachment was almost completely resolved. CONCLUSIONS: ICG dye-enhanced subthreshold micropulsed diode laser photocoagulation appears to be a safe and effective treatment and represents a possible approach for the management of chronic CSC with persistent central serous neuroepithelial detachment. Immediate post treatment ICG angiography, without ICG reinjection, allows documenting the actual number and location of the delivered subthreshold laser applications.

Adult↗

PubMedDate not supplied