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Biomedical subjects

L Cromwell

Publications and source records attributed to L Cromwell.

7 recordsLinked to original sources

Catheter ablation approach on the right side only for paroxysmal atrial fibrillation therapy: long-term results.

We report the long-term follow-up of a right side only catheter ablation approach for paroxysmal AF. Eighteen patients with AF refractory to drugs entered the study. Ablation was attempted in the right atrium only by creating linear lesions based on a specific design including from two to four linear lesions. Induction of AF was attempted before ablation and after placement of the lesions. A septal lesion was performed in nine patients. In ten patients atrial defibrillation thresholds (ADFTs) before ablation and following creation of the linear lesions were compared. After a mean follow-up of 22 +/- 11 months, seven patients had recurrence of AF, and another nine patients experienced atrial flutter or atrial tachycardia. Five patients remained in sinus rhythm without medications and four required the use of drugs. Three patients had sporadic AF and six were in chronic AF. The recurrence rate was similar in patients with and without the septal lesion. However, a cure with right side ablation appeared to be predicted by the presence of disorganized and earlier activity in the high right atrium and crista terminalis. Linear lesions in the right atrium were associated with a lower ADFT (pre 2.6 +/- 04 J vs post 1.7 +/- 0.6 J). In conclusion, in a small number of patients, control of AF can be obtained with a right side only approach. Certain activation patterns may identify patients suitable to this approach. No specific lesion pattern appeared more effective. Right atrial linear lesions resulted in lower ADFT.

Atrial Fibrillation↗

Identifying epileptic foci on contrast-enhanced computerized tomographic scans.

There is a statistically significant association between lateralization of interictal epileptic foci and lateralization of numerical changes between enhanced and unenhanced grossly normal computerized tomographic (CT) scans in the area of the suspected focus. This CT change, lateralized to the side of the focus compared to the homologous opposite brain, is a relative increase in CT values after enhancement. This change is seen in both right or left frontal and temporal foci, and is independent of the time of the last seizure, but is not reliably present if there is a gross abnormality on the CT scan. The technique provides additional evidence of lateralization in epileptic patients without clearly lateralized EEG findings.

Electroencephalography↗

Presurgical embolization of neurogenic hamartoma in an infant. A case report.

The vessels supplying a rare congenital tumor (neurogenic hamartoma) were deliberately occluded by emboli. This extensive tumor presented both in the oropharynx and in the left middle cranial fossa. Using a 3.7 French catheter, Gelfoam emboli suspended in contrast medium were injected into the vessels of the tumor under fluoroscopic visualization. The once vacular tumor was then removed in two stages with little blood loss.

Brain Neoplasms↗