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Biomedical subjects

L Csabay

Publications and source records attributed to L Csabay.

12 recordsLinked to original sources

The relationship between pacifier use, bottle feeding and breast feeding.

OBJECTIVE: To investigate the influence of pacifier use and the introduction of formula milk on breast feeding. METHODS: The mothers of 356 healthy newborn infants who initiated breast feeding while in-patients were interviewed within 3 days of birth and later at 2 and 6 months postpartum. Information regarding previous birth, breast-feeding frequency, pacifier use and the adoption of formula milk were obtained. The data were analyzed using chi2 and Kruskal-Wallis tests. RESULTS: At the end of the second month, 264 (74%) of the mothers were still breast feeding; by the end of the sixth month this had fallen to 236 (66%). Among the 356 mothers, 152 had at least one previous infant, and 132 (86.8%) of them had breast fed a previous infant. Of the women who breast fed their previous infant for more than 2 months, 112 (84.8%) breast fed the current child until the end of the second month and 104 (78.7%) until the end of the sixth month after delivery. Of all investigated patients, 204 were primiparous (57.3%). Of these, 152 (74.5%) breast fed until the end of the second month, and 132 (64.7%) until the end of the sixth month after delivery. Amongthe 204 primiparae, 92 (45%) gave formula to their newborn infants. Forty-four of these 92 mothers (47.8%) had discontinued breast feeding by the end of the second month. Among the 356 newborn infants, 220 used pacifiers at the end of the second month. Within this group, 72 (33%) of the infants did not breast feed, while 148 (67%) did breast feed. Of all investigated mothers, 136 did not give pacifiers to their infants and only eight of these mothers (6%) had stopped breast feeding at the end of the second month. CONCLUSIONS: We found an inverse correlation between pacifier usage and breast feeding. Breast feeding was most common among multiparous mothers.

Breast Feeding↗

Color Doppler ultrasonography in the differentiation of uterine sarcomas from uterine leiomyomas.

OBJECTIVE: The aim of this study was to investigate uterine vascularity in cases of uterine leiomyomas and uterine sarcomas, as well as to determine the efficiency of uterine blood flow analysis in differentiating between them. MATERIALS AND METHODS: Transvaginal color and pulsed Doppler findings obtained from 117 patients with histologically proven uterine leiomyoma and 12 with uterine sarcoma were retrospectively assessed. RESULTS: The mean intratumoral resistance index (RI) and pulsatility index (PI) were significantly lower and the intratumoral peak systolic velocity (PSV) was significantly higher in patients with sarcomas than in patients with uterine leiomyomas. Marked reduction of RI and PI and increased PSV could be found in 14 of the leiomyoma cases which showed large size and/or necrotic, degenerative and inflammatory changes. When a cut-off value of 0.5 for the RI was considered, the detection rate for uterine sarcoma was 67% and the false-positive rate was 11.8%. CONCLUSION: These results suggest that the intratumoral RI detected by color and pulsed Doppler ultrasonography in themselves could be poor for the preoperative differential diagnosis of uterine sarcoma.

Adult↗

Follow-up studies of newborn-babies with congenital ventriculomegaly.

UNLABELLED: The authors present the results of their follow-up studies of data from the last four years on patients with congenital ventriculomegaly. OBJECTIVE: To study the psychomotor and mental developmental outcome of neonates with congenital ventriculomegaly diagnosed prenatally. In addition, patients were also classified into subgroups with subgrouping based on the etiology and complications of congenital ventriculomegaly and on the absence of ventriculoperitoneal shunt placement, and the findings compared between the different subgroups. METHODS: Level 3 fetal ultrasonography was used for the prenatal diagnosis of congenital ventriculomegaly in 30 infants. Using neurological examination and the modified Brunet-Lézine infant test performed postnatal follow-up of motor and sensory development and intelligence, respectively. RESULTS: The results show thirteen symptomless, well-developing patients, ten moderately handicapped patients and seven severely handicapped patients. Newborns with isolated, moderate ventriculomegaly have the best outcome.

Aging↗

Central nervous system anomalies.

The authors review the most common congenital anomalies of the central nervous system (CNS): neural tube defects (NTDs), ventriculomegaly/holoprosencephaly, hydranencephaly, holoprosencephaly sequence, iniencephaly, and microcephaly. They emphasize the importance of the diagnostic tools (biochemical markers of the maternal serum, ultrasound screening, invasive techniques), methods which are complementary to each other.

Central Nervous System↗

Quality assurance in obstetric and gynecologic ultrasound. The Hungarian model.

The majority of physicians performing obstetric scans are radiologists and obstetricians. The radiologist is well trained in imaging but lacks the obstetric background required to interpret information obtained from the scan. The obstetrician is qualified in obstetric knowledge but often lacks the formal imaging training necessary to optimize the pictures. In Hungary, nearly 100% of the physicians who perform obstetric and gynecologic scans are obstetricians. In order to create a standard and to hold together the practitioners in obstetrics and gynecology, as well as to eliminate the serious consequences of clinical malpractice, we organized the Hungarian Society of Ultrasound in Obstetrics and Gynecology in 1992. The Society was established according to the standards of the most skilled obstetricians and gynecologists. In addition to working out the conditions and the standards, the Society provides for its members continuous education, postgraduate training, and monitors the knowledge and level of practitioners. We have established three levels of qualification. Each level requires a medical undergraduate degree. The levels range from basic (A), intermediate (B), to specialist (C). To receive the certificate every user and ultrasound laboratory have to fulfill requirements based on skill as well as equipment and circumstances. The certificates are valid for one year. Every year the practitioner must pass a special examination at the appropriate level. By doing so, the Society provides its members with not only professional support, but ethical and legal security as well.

Certification↗

[Prenatal follow-up of fetal tachyarrhythmia].

A case of fetal supraventricular tachycardia complicated by atrial flutter was recognized in the 26th week of gestation and was successfully treated during pregnancy. Cardiotocography could not generate appreciable result at such a fetal tachyarrhythmia. The intrauterine condition was evaluated by the examination of the Doppler blood flow parameters of the fetal vessels. During follow up strong correlation was found between the blood flow parameters, transplacental therapy and the cardiac function. When repeated and long lasting supraventricular tachycardias were observed, due to the atrial flutter, signs of centralization of the fetal circulation could be monitored as a sign of deteriorating peripheral oxygenation. Parallel to the improvement of the arrhythmia and to the reduction of the supraventricular tachycardia a significant correction of the circulatory parameters could be detected. Based on these experiences, investigation of fetal blood flow parameters is a useful tool in monitoring the intrauterine state of the tachyarrhythmic fetus. It can be concluded that in cases of prenatally diagnosed fetal arrhythmias further pre- and perinatal care should be done in appropriate equipped centers.

Adult↗

[Laparoscopic management of extrauterine pregnancy by salpingotomy].

The classical therapy of tubal pregnancy has been the salpingectomy for decades. Because of infertility problems caused by previous ectopic pregnancies and the organ preserving philosophy the microsurgical salpingotomy became more popular in the seventies. The technical development in the field of gynaecological endoscopy made it possible to perform the salpingotomy even through the laparoscope. The authors report in detail on their technique based on bipolar coagulation, cold knife linear salpingotomy and leaving the tubal wound open for secondary healing. They summarize their preliminary results after the management of nine patients.

Adult↗

Significance of CEA, AFP, SP1 and HCG as tumor markers in ovarian carcinoma.

The significance of CEA, AFP, HCG and SP1 determinations in 85 patients with ovarian cancer were analyzed from the point of view of evaluation of the clinical status of the patients. On the basis of the trials it was stated that a satisfactory correlation between the extension of the tumor and the serum CEA level was observed in 26.6% of the cases. The efficiency of monitoring by systematic CEA tests was found to be 17.3%. The determination of AFP and HCG is useful only in cases of tumors with specific histological structures and in problems of differential diagnostics. The testing of SP1 is of no value in clinical practice.

Biomarkers, Tumor↗

["Maternal floor infarct", simultaneous manifestation of intrauterine fetal retardation and high maternal AFP level].

High AFP level (386.9 ng/ml) at the 16th gestational week in a 23-year old pregnant woman was observed. Fetal malformations or maternal causes could not be detected. Monitoring of fetal development and that of the fetal heart rate showed a worsening intrauterine growth retardation (IUGR). Due to the chronic hypoxia and IUGR cesarean section was performed in the 32nd gestational week and a 960 g female newborn was delivered. Histological examination of the placenta showed signs of maternal floor infarct (MFI): intervillous fibrin netlike deposition with the increase of extravillous trophoblast (X cells) and septal cystic formation. High unexplained AFP level and IUGR can draw attention to the possibility of intrauterine fetal demise, which indicates intensive intrauterine fetal monitoring.

Adult↗