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Biomedical subjects

L Cueto

Publications and source records attributed to L Cueto.

At least 19 recordsLinked to original sources
PubMed2000

Effect of biological suspensions on the position of the binodal curve in aqueous two-phase systems.

This study is concerned with the influence of biological suspension on the position of the binodal curve in aqueous two-phase systems (ATPSs). Three different biological suspensions (i.e., disrupted yeast, E. coli homogenate and fermentation broth from Trichoderma harzianum) were selected and their impact upon ATPS performance was evaluated on the basis of changing volume ratio (Vr) and the position of the binodal curve of biological ATPSs (added with biomass). Biological ATPSs with initial Vr greater than 1 and long (>40%, w/w) tie-line length (TLL), exhibited significant changes in Vr when compared with that from non-biological systems. Such behaviour was associated with the top phase biomass accumulation. It was shown that the addition of the biological suspensions used in this study to ATPSs caused the binodal curve to displace towards the origin, which was associated with the critical contribution of the bio-polymer (present in the systems) to the phase formation. The practical implementation of ATPSs for the purification of biological materials exploiting the information reported in this study is discussed.

Escherichia coli↗
PubMed1983

Echocardiographic evaluation of patients with rheumatoid arthritis.

Mode M echocardiograms in 34 consecutive adult RA patients revealed no significant differences with the findings obtained in 18 normal controls of similar age and sex. One patient had an 11 mm separation between the anterior chest wall and the right ventricle suggestive of a 350 ml pericardial effusion but had no corresponding findings between the posterior left ventricular wall and the pericardium. In this patient the electrocardiogram showed low voltage and the chest roentgenogram an enlarged cardiac silhouette. The differences between these series and other series reported in the literature may reflect ethnic and therapeutic differences between the respective RA populations.

Adult↗
PubMed1979

Echocardiographic changes in pheochromocytoma.

M-mode echocardiography proved to be a useful method in the diagnosis of cardiac changes produced by pheochromocytoma. Findings recorded during a hypertensive crisis included systolic anterior movement of the anterior mitral leaflet, paradoxical septal motion, and prominent excursion of the posterior wall. After surgery, early regression of the chronic effects of hypertension was observed.

Adrenal Gland Neoplasms↗
PubMedDate not supplied

Assessment of left ventricular wall motion.

A new method for the assessment of left ventricular wall motion, using a polar analysis, is proposed. The percent shortening of several radii, labeled at 30 degrees intervals, were plotted against Theta (degrees) and an excellent numerical and visual display of wall motion was obtained. Two methods for correcting the systolic upward shifting of apex were tested. The simplest one uses the intersection of the major and minor axes to realign both the end-diastolic and the end-systolic silhouettes. In the other method ventricular outlines were realigned using anatomical internal markers (diaphragm, ribs, or vertebrae). The intersection of both long axes, whether inside or outside the ventricular silhouettes was used as a pivot point around which the long axes were rotated and the outlines realigned. The mid-point of the long axis was used as a common center. There was no statistical difference in the two methods. The data from 14 normal subjects composed a normal percent shortening vs. Theta graph, which can be used as a frame of reference as compared with abnormal hearts.

Cineangiography↗
PubMedDate not supplied

[Cardiac autonomic neuropathy in the diabetic patient].

The importance of cardiac autonomic neuropathy (CAN) derives from its remarkable frequency and its clinical impact. The clinical features are postural hypotension and resting tachycardia, these abnormalities may be overlooked in a high number of patients asymptomatic. Although rarely life threatening, CAN causes considerable morbidity, which can be ameliorated by its identification and appropriate treatment. Circulatory reflexes were studied in 48 diabetic patients and 14 normal control subjects. Twenty-six of the diabetic patients had normal response. The remaining 22 had evidence of neuropathy and abnormal cardiac response during these tests. Only one patient had postural syncope but he had severe orthostatic hypotension. The others remained asymptomatic. All the control subjects had normal reflexes. Beat-to-beat variation with deep breathing (sinus arrhythmia), carotid body massage and mental stress, were important for the detection of CAN (86, 90 and 90% sensitivity respectively). The Valsalva maneuver and sinus arrhythmia showed 82 and 92% of specificity for the diagnosis of CAN. Our findings suggest that CAN in diabetic patients can be detected by these relatively simple test. We propose a rational approach to the diagnosis. Our method is applicable as a clinical routine examination for cardiac neuropathy.

Adult↗
PubMedDate not supplied

[Scintigraphic criteria for the diagnosis of pulmonary embolism].

The natural history of pulmonary embolism is described, together with the physiopathologic alterations and the clinical manifestations of this disease, correlating these with the various patterns of pulmonary perfusion usually found by lung scintigraphy with 99mTc-MAA in patients with thromboembolic lung disease. By using data found in the literature, the operating characteristics (sensitivity, specificity, and accuracy) and the predictive values of the different scintigraphic patterns, were calculated for populations with different prevalences of pulmonary embolism. It is concluded that perfusion lung scintigraphy is a non-invasive, objective and fast procedure, very sensitive to alterations of the regional blood flow, but that is not specific for embolism. In some cases it can replace pulmonary angiography but in others, its results may indicate the performance of invasive procedures.

Humans↗
PubMedDate not supplied

[Congestive myocardiopathy and early dyastolic closure of the tricuspid valve. Report of a case with acute tricuspidization].

A case with congestive cardiomiopathy and early diastolic closure of the tricuspid valve is presented. This abnormal echocardiographic finding was probably the result of severe tricuspid regurgitation occurring in a restricted right ventricle. The absence of paradoxical septum was determinedly the left ventricular pathology. In this case, echocardiography was more sensitive for the detection of the left sided abnormalities, than the heart cath data.

Cardiac Catheterization↗