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Biomedical subjects

L D Köhler

Publications and source records attributed to L D Köhler.

11 recordsLinked to original sources
PubMed1999

[Squamous epithelial carcinoma-associated necrolytic migratory erythema].

A 59-year-old Caucasian man suffered from persistent disseminated necrolytic skin lesions for 8 months. They failed to respond to a variety of therapeutic regimens but then cleared spontaneously within a few days. After one week an invasive squamous cell carcinoma of the hypopharynx became clinically apparent. At autopsy, the expected glucagonoma often associated with necrolytic migratory erythema was not found.

Carcinoma, Squamous Cell↗
PubMed1998

Congenital lower lip pits--a very rare syndrome? Report of two cases and review of the literature.

A 43-year-old white man and his 12-year-old daughter both displayed congenital lower lip pits. Since Van der Woude's description of this syndrome more than forty years ago, little attention has been given to this uncommon anomaly, probably due to variable expressivity, incomplete penetrance, and recognition of its clinical stigmata. We describe two family members with Van der Woude's syndrome and review its clinical aspects, differential diagnosis, and treatment.

Adult↗
PubMed1997

[Disorders of penile erection and their treatment].

With a prevalence of 1 to 2% among males of reproductive age, erectile dysfunction is relatively common. For the patient and his partner, erectile disorders may represent a highly stressful situation. Frequently, a number of overlapping causes may be found to be responsible, with a psychological component--which may also arise secondarily--being involved in nearly every form of erectile dysfunction. Possible causes, the diagnostic approach and therapeutic options are discussed.

Erectile Dysfunction↗
PubMed1997

[Atypical zosteriform segmental embolia cutis medicamentosa].

A 35-year-old male suffered from an extremely painful embolia cutis medicamentosa. The atypical segmental localization first led to the diagnosis of herpes zoster and an antiviral therapy. Regarding the unusual course of the complication following an intramuscular injection in this case, the question for the real pathomechanisms still remains.

Adult↗
PubMed1997

Embolia cutis medicamentosa.

A 35-year-old man presented with a painful skin necrosis after a deep ventrogluteal injection of diclofenac and dexamethasone for treatment of severe back pain. Immediately after the injection, the patient felt a strong pain just above the injection site. In the following days a remarkable necrosis developed in the upper gluteal region. Topical therapy with antiseptics and a topical corticosteroid cream plus analgesia with tramadole revealed no improvement of the symptoms. We excised the necrotic area. Within 1 day, the patient was without pain.

Adult↗
PubMed1995

[Multiple cutaneous neoplasms in cyclosporine therapy after kidney transplantation].

We report on a 56-year-old renal allograft recipient receiving cyclosporin A immunosuppression. During this therapy he subsequently developed the following cutaneous neoplasms: squamous cell carcinomas, basal cell carcinomas, Bowen's disease, actinic keratosis, sebaceous hyperplasia, a dysplastic naevus and, finally a nodular malignant melanoma. Adverse effects of the cyclosporin A therapy are discussed, with special reference to dermatologic effects and the implications for patient and doctor.

Bowen's Disease↗