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Biomedical subjects

L D Marsh

Publications and source records attributed to L D Marsh.

3 recordsLinked to original sources

Adolescent medicine in pediatric practice: a survey of practice and training.

This study was designed to assess the relation between training in adolescent medicine, during and after residency, and self-reported practice of adolescent medicine. This is a cross-sectional study. A questionnaire was mailed to all members of the South Carolina Chapter of the American Academy of Pediatrics. After 2 mailings, 198 (83%) questionnaires were returned. Adolescent medicine training in residency was associated with more adolescent patients enrolled in a practice (P < 0.01) and more adolescent patient visits (P < 0.01) but not with an increase in perceived competence in the practice of adolescent medicine. Adolescent medicine continuing medical education was associated with seeing more adolescent patients and with increased competence in many areas, including contraceptives, suicide, and school problems (P < 0.05). training in adolescent medicine during and after residency is associated with treating more adolescent patients. Continuing medical education also is associated with increased perceived competence in areas related to adolescents.

Adolescent Medicine↗

Effects on the efferent ducts in Macaca mulatta.

Immunopathologic findings in efferent ducts of 36 rhesus macaques vasectomized as many as 12 years earlier and of 11 age-matched control animals were compared. Electron-microscopic observation of these ducts revealed changes after vasectomy. The epithelium shortened from a prevasectomy height of 25 mu to 14 mu as the ducts stretched after vasectomy. The number of sperm and macrophages in the lumen increased. The basement membrane was 300-700 A wide in nonvasectomized animals but several times that in animals vasectomized 6 or more years before; the mean width significantly increased with time after vasectomy. Numerous electron-dense immune complexes were found within the thickened lamina in 33% of vasectomized animals and in none of the controls. The mean size of the electron-dense areas varied from 0.01 sq mu in a monkey vasectomized 3 years earlier to 0.18 sq mu in an animal vasectomized 7 years earlier; the mean area significantly increased with time after vasectomy. Frozen sections of testis and epididymis were evaluated through the use of fluorescein-conjugated antibodies. Of the nonvasectomized controls, 18% showed immune deposits. Of the vasectomized animals, 53% revealed C3 deposition in the basement membrane surrounding the efferent ducts. The presence of electron-dense deposits plus the finding of putative immune complexes as revealed by immunofluorescence suggested that vasectomy enhances leakage of sperm antigens, particularly in the region of the efferent duct.

Animals↗

Bulimia and dextromethorphan abuse. A case study.

The comorbidity of bulimia and substance abuse is significant. The substance that is abused may vary and the abuse potential for nonillicit substances may be overlooked. This paper presents the first case reported of dextromethorphan abuse and bulimia. It demonstrates the complexity of assessment and treatment of bulimia and substance abuse of over-the-counter medications.

Adolescent↗