Intraventricular conduction defects: clinical implications.
Explore the source record for details and available documents.
Heart Block↗
Biomedical subjects
L D Ostrander
Publications and source records attributed to L D Ostrander.
Independence of serum lipid levels and dietary habits. The Tecumseh study.
Serum cholesterol and triglyceride levels were correlated with dietary habits of 4,057 adult participants in a prospective epidemiologic survey of cardiovascular disease in Tecumseh, Mich. Frequency of consumption of 110 different food items was determined for each participant and average weekly consumption rates of foods high in fat, sugar, starch, and alcohol content were calculated. Frequency of consumption of these nutrients was then correlated with serum cholesterol and triglyceride levels of individual subjects. Serum cholesterol and triglyceride values were not positively correlated with selection of dietary constituents. Positive correlations between serum lipid levels and adiposity were statistically significant. These findings suggest that serum cholesterol and triglyceride levels among Americans are more dependent on degree of adiposity than on frequency of consumption of fat, sugar, starch, or alcohol.
Adult↗
Daily nutritional intake and serum lipid levels. The Tecumseh study.
To determine the influence of diet on serum cholesterol and triglyceride levels among adults, 24-hr dietary recall interviews were conducted among 957 men and 1,082 women resident in the community of Tecumseh, Michigan. Trained interviewers obtained detailed description of all foods consumed during 24 hr before venipuncture for lipid determination. Using a list of nutritional composition of 2,706 foods prepared from standard references, nutritionists determined quantities of all nutrients common to the American diet which were consumed by each participant according to a 24-hr diet record. For analysis, men and women were grouped into lower middle, and upper tertiles according to serum cholesterol and triglyceride levels. The mean daily consumption of each dietary component was virtually identical in all tertiles for men and women but differed between sexes. Cholesterol and triglyceride levels were unrelated to quality, quantity, or proportions of fat, carbohydrate, or protein consumed in the 24-hr recall period.
Adult↗
Coronary risk factors in a community. Findings in Tecumseh, Michigan.
In the Tecumseh study population examined from 1967 through 1969, 1457 men and 1607 women were separated into young (20-39 years), middle (40-54 years), and old (past 55 years) age categories. A subset of the study population, 183 men and 200 women who were repeatedly hyperglycemic according to a modified glucose tolerance test, were divided into the same age groups. Means and standard deviations of adiposity index, serum cholesterol, serum triglyceride, blood glucose, and systolic blood pressure were calculated for the total population and hyperglycemics. Correlation coefficients were determined for the relationship between adiposity index and each of the other variables and between paired variables exclusive adiposity index. Correlation coefficients for the latter relationships were recalculated after adjustment for the effect of adiposity. Means of variables were higher in middle and older age categories than in young age categories in both sexes, but the greatest incremental increases occurred between the young and middle-aged groups of men and between middle and old age groups among women. Men had significantly higher mean triglyceride and systolic blood pressure values than women in young and middle ages. Except for the cholesterol-triglyceride association, lipids, glucose, and systolic blood pressure were more highly correlated with adiposity than with each other. Correlations between variables were reduced by adjustment for adiposity. Hyperglycemics had higher mean adiposity indexes, serum lipids, and systolic blood pressures and generally higher correlations of variables than the entire study population. Much of the interrelationship of variables among hyperglycemics was associated with adiposity. Among men, higher mean triglyceride and systolic blood pressure levels, more frequent coexistence of risk factors, and a tendency to have large incremental increases in mean variables between young and middle age probably contribute to greater male susceptibility to ischemic heart disease. Levels of variables in the population and aggregation of coronary precursors in individuals are related to adiposity and hyperglycemia.
Adult↗
Diabetes among men in a general population. Prevalence and associated physiological findings.
A random sample of 281 men, aged 30 through 69, resident in the community of Tecumseh, Mich, was studied with the use of standard glucose tolerance tests, including serum insulin assays and fasting serum lipid concentrations. Diagnoses of diabetes and probable diabetes were made according to a modification of the criteria of Fajans and Conn. Prevalence of diabetes and probable diabetes was considerably higher among men aged 40 through 49 than among those aged 30 through 39, but it increased little in the 50-through-59 and 60-through-69 age groups. Lean nondiabetics and probable diabetics had similar mean systolic blood pressures and similar mean levels of serum cholesterol, serum triglycerides, and serum insulin, but fat probable diabetics had much higher mean serum lipid and serum insulin concentrations that fat nondiabetics. Adiposity grouping discriminated by variable levels less well between diabetics and nondiabetics.
Adult↗