PubMed Health⌕ Search

Biomedical subjects

L Danielli

Publications and source records attributed to L Danielli.

14 recordsLinked to original sources

Transurethral water-induced thermotherapy for the treatment of benign prostatic hyperplasia: a prospective multicenter clinical trial.

PURPOSE: We evaluate the effectiveness and safety of transurethral water-induced thermotherapy for the treatment of lower urinary tract symptoms of benign prostatic hyperplasia (BPH). MATERIALS AND METHODS: A total of 125 patients with lower urinary tract symptoms due to BPH were enrolled at 8 study centers. Pretreatment evaluation included determination of International Prostate Symptom Score (I-PSS), peak urinary flow rate and quality of life score. Patients also completed a sexual function questionnaire. Patients were evaluated 3, 6 and 12 months after water-induced thermotherapy. RESULTS: Significant improvements in I-PSS, peak urinary flow rate and quality of life score were observed as early as 3 months after water-induced thermotherapy. At 12 months I-PSS had improved by a median of 12.5 (95% confidence interval 11.5 to 13.5) versus baseline, peak urinary flow rate by 6.4 ml. per second (5.6 to 7.5) and quality of life score by 2.5 (2.0 to 2.5). I-PSS, peak urinary flow rate and quality of life score improved by 50% or more at 12 months in 61.5%, 71.3% and 71.6% of patients, respectively. No adverse impact of water-induced thermotherapy on sexual function was noted, and preexisting discomfort during ejaculation and interference in sexual function due to lower urinary tract symptoms were significantly ameliorated after treatment. Serious adverse events were infrequent and manageable. CONCLUSIONS: Water-induced thermotherapy significantly alleviates lower urinary tract symptoms of BPH, increases peak urinary flow rate and enhances patient quality of life. This novel catheter based, minimally invasive treatment is easily administered in the outpatient setting. Water-induced thermotherapy holds promise as a useful and cost-effective option for the clinical management of BPH.

Aged↗

Minimally invasive surgical treatment of female stress urinary incontinence.

The purpose of this study was to evaluate the safety and efficacy of a new minimally invasive surgical procedure for the treatment of female stress urinary incontinence (SUI). Four miniature bone anchors, each attached to a suture, are inserted transvaginally into the retropubic bone using an inserter on each side of the urethra without opening the vaginal mucosa. Tying the suture on each ipsilateral side creates colposuspension, as is the aim of previously described procedures such as the Marshall-Marchetti-Krantz. Sixty-one women (mean age 52+/-SD 9.9 years) with a mean follow-up of more than 12 months (range 12-30 months) were treated for SUI. Fifty patients (82%) are dry, 7 (14%) reported great improvement and 4 are considered surgical failures. The data presented suggest that our new minimally invasive procedure provides an effective treatment for female SUI. Its main advantages over other procedures are the transvaginal approach and short operating time.

Female↗

Serious complications of routine ritual circumcision in a neonate: hydro-ureteronephrosis, amputation of glans penis, and hyponatraemia.

A 13-day-old infant developed bilateral hydroureteronephrosis, severe hyponatraemia, hyperkalaemia, and acidosis, as a result of urethral damage following circumcision. The hydroureteronephrosis and biochemical abnormalities normalized after resolution of the penile injury. Conclusion. Infants with urinary retention following circumcision may develop hydro-ureteronephrosis and electrolyte disturbances. An awareness of the potential dangers of circumcision may help to limit its complications.

Ceremonial Behavior↗

[Transurethral procedures with sacral anesthesia].

Sacral anesthesia is a safe and effective procedure which we have used in 28 resections for benign prostatic hypertrophy, and in 42 resections of bladder tumors, 7 of them in women. The average age was 69 years. Average time for prostatic resection was 49 minutes and for bladder tumors, 23. Recovery from anesthesia averaged 78 minutes in both groups. In 44.3% of the patients there was no need for other medication during operation. Hemodynamic changes were minor and were controlled by fluid replacement in a third of the patients. Complications included convulsions (2 patients), severe headache (2), arrhythmias (5) and skin rash (1). There were no late sequelae. 0.5% marcaine was the most effective drug. The success rate was 77.1% in both groups; failures were due to technical difficulties.

Aged↗

Relationship of blood groups and bladder cancer. A retrospective study.

A retrospective study to evaluate the relationship of blood groups of 96 patients with transitional cell carcinoma of the bladder in Israeli population, reports that patients with blood group O had higher grade tumors and higher recurrence rates than the other blood groups, without a difference in the mortality rates.

Aged↗

Recurrent hematuria during multiple pregnancies.

A 33-year-old woman presented left ureteral gross hematuria under two conditions: before the second trimester of her last three gestations, and after therapy with an oral contraceptive. We believe that left renal vein varicosities, influenced by mechanical and hormonal factors, produced the hematuria.

Adult↗

[The chorionic gonadotropin hormone: possible cause of seminoma?].

Two cases of seminoma that appeared in young males who had received high dosages of Chorionic Gonadotrophin Hormone (HCG) as treatment for secondary sterility are presented. The authors suggest that this treatment has an etiological or at least permissible role in the development of these tumors. Careful examination with testicular biopsy is recommended on all males receiving hormone treatment for oligospermia, and follow-up should continue after cessation of the treatment.

Adult↗

The search for a consensus for early detection of bilateral seminoma.

A case of bilateral seminoma of the testis is presented that occurred after a lag period of six years following right orchiectomy, even with correct cobalt therapy. The question of early detection of seminoma in the other testis is posed. A common consensus for repeat biopsies to detect new tumor growth should be determined.

Adult↗