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Biomedical subjects

L De Medinaceli

Publications and source records attributed to L De Medinaceli.

3 recordsLinked to original sources

How to correctly match 175,000 neurites: two postulates for a quick solution.

I propose two postulates that allow precise matching of an indefinite number of neurites when repairing a transected nerve. The first one, based on the principle of de Saint-Venant, indicates how to keep nerve fibers in proper longitudinal alignment, by diverting stress to an appropriate distance from the tip of the stumps. The second postulate, based on the symmetrical mechanical resistance of the stumps, indicates how to restore correct transversal alignment of the fibers, by circularizing the severed nerve extremities.

Biomechanical Phenomena↗

Is vigor of regeneration a key factor in recovery from peripheral nerve injuries?

The nerve-growth-promoting effects of the tricyclic antidepressant, imipramine, were tested on the sympathetic ganglion of chickens and on the sciatic nerve of rats. A powerful neuronotrophic action was observed in vitro, but the utilization of the drug in vivo did not modify the functional recovery from a crush lesion.

Animals↗