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Biomedical subjects

L Derrick

Publications and source records attributed to L Derrick.

5 recordsLinked to original sources
PubMed1990

Thyroid cancer: a computer-assisted review of 5287 cases.

Retrospective computer analysis of all reportable cases of thyroid cancer for the Rocky Mountain Cancer Data Systems between 1973 and 1983 was undertaken. Follow-up data were available for periods of 5 to 10 years. All major histologic findings are reviewed with regard to distribution, prognostic factors, mortality rates, and some treatment modalities. Interesting observations determined by this study include: (1) the significantly greater mortality rates seen in patients with thyroid cancer after 50 years; (2) the lack of increased mortality rates in young patients with differentiated cancer; (3) the poorer prognosis of male patients of equivalent age to female patients in all histologic types of cancer in the first 5 years; (4) the lack of sexual difference in influencing mortality rates after the first 5 years in differentiated cancers and lack of sex as a prognostic indicator in undifferentiated cancers; (5) the excellent prognosis of patients with localized differentiated and medullary cancers and a better-than-expected prognosis in the undifferentiated group; (6) the clear need for combined therapy (surgery and irradiation) in regional medullary cancer; (7) the observation that localized thyroid lymphoma had a higher mortality rate than had regional thyroid lymphoma; and (8) a significantly higher mortality rate in patients older than 79 years with differentiated cancer.

Adenocarcinoma↗
PubMed1987

Treatment of hypopharyngeal carcinoma: a 10-year review of 1,362 cases.

A computer search of cancer patients enrolled in the Rocky Mountain Cancer Data System between 1973 to 1983 revealed 1,362 patients with hypopharyngeal cancer, 1,208 of whom could be staged by the American Joint Committee on cancer staging criteria. Stage I and II patients comprised 17.5% while 71% were either stages III or IV. The distant metastatic rate in advanced stage patients was 24%. Survivals for all treated patients were 65% at 1 year, 33.5% at 3 years, and 25% at 5 years. Three-year survivals were 54.5% for the surgery only group, 41.6% for the combined therapy group, and 17.7% for the irradiation only group. Five-year survivals for the surgery only group were 39.8%, combined therapy, 31.8%, and irradiation only 11.5%. These figures are actuarially corrected. Twenty-two percent of combined therapy patients had preoperative irradiation versus 78% who had postoperative irradiation. There was no statistically significant difference seen between these two groups.

Carcinoma↗
PubMedDate not supplied

Accessing NCI's SEER cancer data base with SeerQuery and CD-ROM.

The National Cancer Institute operates the Surveillance, Epidemiology, and End Results (SEER) cancer data base. SEER data are obtained from participating population-based registries that monitor cancer incidence and patient survival in a representative 10 percent sample of the general population. The data cover all cancers (except superficial skin cancers) in the defined regional populations. SeerQuery is a personal computer program for accessing that data on IBM-compatible personal computer compact diskettes in read-only memory (CD-ROM) form. SeerQuery facilitates rapid access to cancer data at minimal cost and effort to the user. SeerQuery is menu-driven, enabling physicians and other health care professionals to query the data base directly. They can use the data to determine cancer frequency, perform cross-tabulation, determine incidence, and calculate survival using such variables as primary cancer site, histologic type, stage, sex, age, and race. The comprehensive data base lacks many selection biases that are inherent in data reported from other sources. SeerQuery has applications in professional education and in cancer control program planning and resource allocation.

Adult↗