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Biomedical subjects

L Domellöf

Publications and source records attributed to L Domellöf.

At least 91 records · Page 5Linked to original sources

Angiography of the testicular artery. II. Cryptorchism and testicular agenesis.

A selective angiography of the testicular artery was performed in 7 boys and 7 men without a palpable testicle in order to localize cryptorchid testes or to establish testicular agenesis. The examination could be carried out in all cases, and the angiographic diagnosis was confirmed at operation and at a subsequent microscopy in the 12 cases hitherto operated upon. The width of the artery and its branches are also presented.

Adolescent↗

Lipid islands in the gastric mucosa after resection for benign ulcer disease.

Lipid islands in the gastric mucosa are macroscopically well demarcated white or yellow-white patches, microscopically composed of accumulations of lipid-filled macrophages. The occurrence of lipid islands has not previously been linked to gastric surgery. This study presents the prevalence of lipid islands after Billroth I and Billroth II resection as well as in a nonoperated control group. Gastroscopy and multiple biopsies were performed at selected intervals after surgery. The occurrence of single or multiple lipid islands increased with the postoperative time, independent of the original ulcer disease or the type of operation performed. In nonoperated patients, lipid islands were found in 6.3%, and approximately the same prevalence was found 1 to 3 years after gastric surgery. A much higher prevalence was found 10 to 15 years postoperatively, and 23 years after Billroth II resection 60% of the patients demonstrated lipid islands. At repeated gastroscopic examinations over a period of 1 to 2 years, no certain changes in number, size, or distribution of the lipid islands were seen. The etiology of lipid islands is unknown, but intestinal-gastric reflux may be the most plausible etiological factor.

Adult↗

Late precancerous changes and carcinoma of the gastric stump after Billroth I resection.

Carcinoma of the gastric remnant after resection for benign ulcers is regarded as a rare complication after Billroth I resection. In seventy-four patients reexamined by gastroscopy and multiple biopsies ten to twenty-two years after gastric resection four cases of cancer of the gastric stump were diagnosed and the patients operated on. Another eight patients had regenerative polyps and one patient had a tubular adenoma. The histologic findings in gastroscopic biopsy specimens from the gastric stoma and fundus are compared. Possible precancerous changes and etiologic aspects are discussed briefly. Repeated gastroscopy is recommended starting about ten years after gastric resection for benign ulcers.

Adenocarcinoma↗

Dysplasia of the testis and epididymis.

Various congenital malformations of the testis and the seminal pathways are illustrated by 10 cases. Though these malformations are often free from symptoms, an increasing number of them are now being discovered in connection with investigations of male infertility. In cases of azoospermia where testicular biopsies show complete spermatogenesis, surgical exploration is indicated. Some of these malformations may then be treated by surgery, with fairly good prospects of restored fertility.

Abnormalities, Multiple↗

Late occurrence of precancerous changes and carcinoma of the gastric stump after Billroth II resection.

In a prospective study, patients resected for benign ulcer disease 20 years previously were followed up. Of 100 patients operated with anterior gastro-jejunal anastomosis and entero-anastomosis 51 were examined with gastroscopy and multiple biopsies taken from the stoma and gastric fundus. Acute and chronic inflammation of varying degrees were general findings. Single or multiple polyp-like changes at the stomal ring were found in 4 cases and in one patient an asymptomatic low differentiated, adenocarcinoma was found. Intestinal metaplasia and cystic dilatation of the gastric glands were most frequently found in the stomal biopsies and less frequent in biopsies taken from the gastric fundus. In order to evaluate these possibly precancerous changes all patients will be continuously controlled. Nineteen patients were dead at the time of the follow-up. One of these had died of carcinoma of the gastric remnant.

Adenocarcinoma↗

Ectopic liver lobule with portal cirrhosis.

A patient who had an ectopic liver attached to the gallbladder is reported. Angiography, scintiscanning, and routine palpation at laparotomy did not reveal the ectopic liver. Advanced liver cirrhosis was found in autopsy and the same changes were seen in the ectopic liver. The embryology, localization, symptoms and incidence of ectopic liver lobules are discussed.

Adult↗