Optic and peripheral neuropathy in Cuba.
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Biomedical subjects
Publications and source records attributed to L Du Bois.
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Solubility measurements, seeded crystal growth kinetics, solution depletion adsorption studies, nucleation observations, zeta potential measurements, and measurements of in vivo intrarenal crystallization all failed to show that either oxipurinol or allopurinol riboside interacts with calcium, oxalate, or whewellite (CaC2O4.H2O) at concentrations expected in therapeutic situations. We conclude that at therapeutically expected concentrations, oxipurinol and allopurinol riboside do not affect crystallization of calcium oxalate.
The adsorption of heparin on sodium acid urate powder suspended in aqueous solution was found to be dependent upon the concentration of Ca2+ and Mg2+. It was concluded that heparin adsoprtion on sodium acid urate powder can occur in urine. Speculations are made about the relevance of these observations to calcium oxalate urolithiasis.