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Biomedical subjects

L E Klusman

Publications and source records attributed to L E Klusman.

4 recordsLinked to original sources

Neuropsychological abnormalities in asymptomatic HIV seropositive military personnel.

Comprehensive neuropsychological evaluations were performed on 103 asymptomatic, HIV-1 antibody seropositive U.S. Army males to assess cognitive impairment. The sample was demographically heterogeneous. Using established clinical norms, 37.9% of the sample had an abnormal neuropsychological exam. Impairment varied as a function of ethnic group but not as a function of emotional distress or disease status determined by the Walter Reed staging system. We discuss our high frequency of impairment relative to other studies in terms of subject characteristics, methodological factors, and the possibility that subjects of average intellectual ability possess inadequate capacity to moderate neurobehavioral consequences of the virus.

AIDS Dementia Complex↗

Analysis of errors on the Trail Making Test.

This study was designed to determine whether the number and/or types of errors on the Trail Making Test differentiated head-injured and normal control subjects. Errors on Part B were categorized into two types of shifting errors (from number to letter and from letter to number) and two types of sequencing errors (number and letter). Subjects consisted of 133 head-injured patients and 145 normal controls. Analysis showed that the frequency of errors on Parts A and B did not differ significantly between the groups nor did the percentage of subjects making errors. Total shifting and sequencing errors also did not differentiate between the two groups. Although head-injured subjects were more likely than controls to err in shifting from letters to numbers, this finding was of no apparent clinical usefulness. The discriminative value of time scores was confirmed.

Brain Damage, Chronic↗