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Biomedical subjects

L E Magargal

Publications and source records attributed to L E Magargal.

At least 55 records · Page 3Linked to original sources
PubMed1986

Chronic exudative ischemic superior temporal-branch retinal-vein obstruction simulating Coat's disease.

A 62-year-old white man presenting with retinal telangiectasia, subretinal exudates, and a circumscribed nonrhegmatogenous retinal detachment secondary to an ischemic superotemporal-branch retinal-vein obstruction is described. Sectorial-scatter argon laser photocoagulation resulted in complete flattening of the retina and a return of visual acuity to 6/12 (20/40). Although lipid exudates and retinal detachment secondary to retinal venous occlusion have previously been reported, our case had the additional finding of marked retinal telangiectasia suggesting adult Coat's disease. This case indicates that a retinal venous occlusion can produce a capillary response simulating the characteristic features of Coat's disease.

Diagnosis, Differential↗
PubMed1985

Intravenous digital subtraction angiography and its role in ocular vascular disease.

One hundred patients with ocular occlusive vascular disease were studied by intravenous digital subtraction angiography (IV DSA). In 17 patients with transient monocular blindness, 65% showed ipsilateral carotid atheroma. The degree of carotid stenosis was greater than 70% in eight of the 17 patients. Severe unilateral or bilateral stenosis was demonstrated in 70% of ten patients with chronic retinal artery obstruction, ie, venous stasis retinopathy or orbital hypoxia. An ipsilateral carotid artery source of emboli or substantial degree of stenosis was documented in 50% of 48 patients with acute retinal artery obstruction. Little or no carotid disease was found in 72% of 25 patients with retinal vein obstruction. The greatest value of IV DSA is in the management of patients with transient monocular blindness.

Aged↗
PubMed1985

Microcomputer applications in pathology research.

In a study of over 700 cases of uveal melanoma on file in the Department of Pathology of Wills Eye Hospital, a low-cost microcomputer using commercially available software (without modification) was used to: word process and edit this manuscript, create a patient file storage and retrieval system including the ability to create subfiles, merge files, and interchange file types, plot data points in several different graphic formats, transcribe and store information from microscopic tissue sections containing intraocular melanomas, and solve complex equations including statistical analysis. The results showed that over 150 different ophthalmologists contributed specimens to this data base. The mean age of the patients studied was 57 years and the tumors were evenly distributed according to sex and laterality of the eye. This study illustrates the feasibility of using a low-cost microcomputer and commercially available software in the study of a large patient data base.

Computers↗
PubMed1985

Diabetic retinopathy under age 20. A review of 71 cases.

A review of the fluorescein angiograms on 4547 diabetic patients with clinically suspected retinopathy was performed. Although only 26 (1%) of the 2013 males and 45 (2%) of the 2534 females were less than 20 years old (71 patients total), proliferative diabetic retinopathy (PDR) was diagnosed in 14 females (31%) and 4 males (15%). The youngest patient, a 13-year-old boy with diabetes for eight years, presented with severe proliferative diabetic retinopathy in both eyes as documented angiographically. He showed no evidence of other systemic complications of diabetes. A review of the literature revealed one other case of proliferative diabetic retinopathy in a patient this young; a 13-year-old girl who was nephrotic and hypertensive upon presentation. This study emphasizes the importance of having prepubescent and teenage diabetics examined for the presence of retinopathy.

Adolescent↗