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Biomedical subjects

L E Probst

Publications and source records attributed to L E Probst.

29 records · Page 2Linked to original sources

Phacoemulsification with aspirated or retained Viscoat.

Endothelial cell counts, morphology, and 24-hour postoperative intraocular pressure (IOP) changes were measured in 55 consecutive patients (60 eyes) who had uncomplicated phacoemulsification and posterior chamber lens implantation with either aspirated (30 eyes) or retained (30 eyes) Viscoat (sodium chondroitin sulfate-sodium hyaluronate). The surgical technique was standardized in all cases. Endothelial cell loss was almost identical in the aspirated and in the retained groups (8.8% and 8.7%). Postoperative pleomorphism was significantly less in the retained Viscoat group than in the aspirated group, suggesting a possible protective effect of the retained viscoelastic. Corneal thickness increased significantly in the retained Viscoat group, but this was not significant clinically. The retained Viscoat group had more patients with a postoperative IOP greater than 30 mm Hg and a greater mean increase in postoperative IOP, although the difference between the groups was not significant. The IOP changes may have been caused by blockage of the trabecular meshwork by the retained Viscoat. The results suggest that Viscoat can be retained after cataract surgery if the surgeon is prepared for a greater 24-hour postoperative increase in IOP.

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Diagnosis of congenital syphilis in adults presenting with interstitial keratitis.

In the antibiotic era the ophthalmologist has become less familiar with the diagnosis of congenital syphilis. The recognition of this disease is crucial, as neurosyphilis or cardiovascular syphilis will develop in a substantial number of patients with latent congenital syphilis without the appropriate treatment. We describe eight patients aged 60 years or more who presented with refractive problems in whom congenital syphilis was subsequently diagnosed for the first time. One patient was found to have neurosyphilis and the highest VDRL result ever recorded by the London Public Health Laboratory. Seven patients required extensive antibiotic therapy, and three subsequently underwent successful ocular surgery. These cases illustrate the importance of recognizing this treatable disease.

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Corneal endothelial and intraocular pressure changes after phacoemulsification with Amvisc Plus and Viscoat.

A prospective, randomized, observer-marked study was conducted to compare corneal endothelial and intraocular pressure (IOP) changes after cataract surgery with the viscoelastic agents Amvisc Plus and Viscoat. Forty-nine patients (50 eyes) who had uncomplicated phacoemulsification and implantation of a posterior chamber intraocular lens were randomly assigned to either Amvisc Plus (25 eyes) or Viscoat (25 eyes) groups. Surgical technique was rigidly standardized in all cases. No significant difference in endothelial parameters or postoperative IOPs measured at 24 hours, one week, and two months was detected by analysis of variance between the Amvisc Plus and the Viscoat groups. Visualization was difficult with Viscoat because of its tendency to retain bubbles. Phacoemulsification energy was related to a loss of endothelial density, regardless of the viscoelastic used. The postoperative beta blocker may have contributed to the lower average postoperative IOP than has been reported.

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