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Biomedical subjects

L E Sweeney

Publications and source records attributed to L E Sweeney.

12 recordsLinked to original sources
PubMed2005

Neck masses in children.

Infants and children with neck masses frequently present to the radiologist for further evaluation. The role of the radiologist is to differentiate between conditions using imaging modalities such as ultrasound with colour Doppler, CT and MRI. Where appropriate, the radiologist will also stage lesions for management purposes and aid in guiding aspiration or biopsy. This paper presents a pictorial review of paediatric neck masses and their imaging features. Particular emphasis is applied to the anatomical site of the mass to aid in differential diagnosis. It must be emphasised that the radiological findings should always be interpreted in conjunction with the patient's age, the clinical history and the findings on physical examination.

Abscess↗
PubMed2000

Elevated renal rind.

We describe the findings from a group of five infants ranging in age from 3 weeks to 13 months who had shock of differing causes. In each case, sonographic evaluation of the abdomen revealed bilateral perirenal hyperechoic bands several millimeters thick, surrounding a thin, hypoechoic rim of fluid. The findings were identified during the acute phase of each child's illness and persisted after the patient's condition had clinically improved, eventually resolving in the three surviving children. We have dubbed this sign the "elevated renal rind." We believe that the changes are likely secondary to systemic inflammatory mediators and do not reflect localized intraabdominal disease.

Acute Disease↗
PubMed1993

Hypophosphataemic rickets after ifosfamide treatment in children.

Ifosfamide is a derivative of cyclophosphamide and is used to treat malignant tumours. One of its side effects is nephrotoxicity. Three children with previously normal renal function, who received ifosfamide for the treatment of Ewing's Sarcoma and subsequently developed hypophosphataemic rickets, are described.

Child↗
PubMed1991

Initial investigation of childhood urinary tract infection: does the plain abdominal X ray still have a role?

To reassess the plain abdominal X ray (AXR) in the initial investigation of childhood urinary tract infection, radiologists from four paediatric units prospectively collected data on the yield from the AXR in 683 children. Five children had renal calculi. All were detected on ultrasound, but one was not visible on the initial AXR. Four spinal abnormalities were identified, none of which prompted any action by the clinician involved. While the costs, in both financial and radiation risk terms, may be small, the benefit of the AXR appears equally small. Where expert paediatric ultrasonography is available we would recommend that the AXR be reserved for patients with haematuria, loin pain, family history of calculus disease, or where further urinary tract infection occurs despite a normal ultrasound scan.

Adolescent↗
PubMed1990

Osteopenia and phenylketonuria.

Trabecular bone mineral content was assessed by quantitative computed tomography in eleven young adults with phenylketonuria who had been treated from early childhood with a diet restricted in natural protein and supplemented with amino acids, minerals and vitamins. There was a significant reduction in the bone mineral content of patients compared with the normal population. Prospective studies are indicated in younger patients to ensure optimum bone mineralisation is achieved by adulthood.

Adult↗
PubMed1987

Contrast examination of cerebrospinal fluid shunt malfunction in infancy and childhood.

The technique of contrast examination of the common types of cerebrospinal fluid (CSF) shunts is described. The findings in 250 shuntograms are analysed and the results discussed. The most common cause of shunt malfunction was shunt blockage. Errors of interpretation occurred in 16 shuntograms and were more frequent in Pudenz systems than in Spitz-Holter. The technique is simple, safe, accurate and does not require special apparatus. There was only one serious complication in 250 shuntograms. It is particularly useful when the anterior fontanelle has closed.

Cerebrospinal Fluid Shunts↗
PubMedDate not supplied

Dosimetric evaluation of a variable field electron beam applicator.

A commercially available variable electron beam applicator designed for the Phillips SL-75/20 linear accelerator was tested for possible clinical use. The basic design of this collimator consists of four movable L-shaped stainless steel blades forming the corners. In addition, four smaller fixed blades of the same material and thickness fill in the sides. Film placed in polystyrene phantoms were exposed in all experiments. Field size, field flatness, beam homogeneity and penumbra measurements, all indicated that the applicator is acceptable for clinical use. However, for use with large field sizes and/or high energy electron beams some minor modifications are suggested.

Electrons↗