Biomedical subjects

L Engell

Publications and source records attributed to L Engell.

2 recordsLinked to original sources

PubMed2000

Randomised clinical trials in the Scandinavian Journal of Rheumatology.

OBJECTIVE: To identify all reports of randomised clinical trials in the Journal and compare our findings with reports available in Medline. METHODS: We handsearched the Scandinavian Journal of Rheumatology with supplements for the years 1955-1997 to identify reports of randomised clinical trials and controlled clinical trials. RESULTS: We identified 445 trial reports. In Medline, 134 of these trials (30%) were indexed as randomised or controlled trials; an additional 50 trials (11%) were available in Medline but were indexed differently. Thus, 261 of the trials (59%) we identified were not indexed in Medline; most of these trials were published in supplements to the Journal. CONCLUSION: Handsearching of medical journals for randomised trials can be a worthwhile effort. Clinicians and patients will become better informed about the value of different treatment options and researchers will reduce their risk of performing trials that are unnecessary.

Humans↗

PubMed1995

Flow measurements with digital subtraction densitometry in a steady flow experimental model.

Computerized densitometry was applied on digital subtraction series for measuring flow rates, 600 to 2,000 ml/min, in model experiments, using contrast medium as indicator substance. A total of 962 measurements were performed, employing the Stewart-Hamilton dilution technique, as well as direct measurements of velocity of the indicator bolus between 2 measuring sites. Results with the dilution technique were closely correlated with true values, but slightly lower (mean 8%), presumably because of sedimentation of contrast medium. Measurements based on bolus velocity were most accurate when the bolus passage was defined by points near the gravity line of the area under the concentration curve. Use of more easily identified curve points, e.g. the time of curve maximum, tended to yield too high values due to flow laminarity with a high-velocity leading edge of the indicator. Variation in repeated measurements on any single image series was attributed to the low sampling rate.

Absorptiometry, Photon↗